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췌장의 파골세포 모양 거대세포종양 1예

Other Titles
 A Case of Osteoclast-like Giant Cell Tumor of the Pancreas 
 조상형  ;  천재희  ;  박중원  ;  홍은경  ;  이우진  ;  박상재  ;  김성훈  ;  박홍석  ;  이상원 
 Korean Journal of Gastroenterology, Vol.45(6) : 441-445, 2005 
Journal Title
Korean Journal of Gastroenterology(대한소화기학회지)
Issue Date
Osteoclast-like giant cell tumor ; Pancreatic neopla는
Osteoclast-like giant cell tumor ; Pancreatic neopla는
Osteoclast-like giant cell tumor of the pancreas is a very rare tumor. Despite their striking morphologic resemblance to certain mesenchymal tumors of bone and tendon sheath, it has been suggested that these tumors may arise from epithelial precursors. This unusual tumor presents in the 6th or 7th decade with a nearly equal gender ratio. Pure forms of osteoclast-like giant cell tumor have a better prognosis because they have a predilection to local spread, are slower to metastasize and rarely metastasize to lymph nodes, but these forms are very rare. We present an osteoclast-like giant cell tumor arising in the body of the pancreas in a 71 year-old male patient. The tumor was composed of two major cell types: atypical mononuclear cells and abundant osteoclast-like multinucleated giant cells. Immunohistochemical studies showed that atypical cells were strongly reactive for vimentin and focally reactive for cytokeratin. In contrast, the giant cells were immunoreactive for CD68, but negative for cytokeratin. Three months later, the tumor size increased and liver metastasis was newly developed. He died at 11 months after the diagnosis.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Cheon, Jae Hee(천재희) ORCID logo https://orcid.org/0000-0002-2282-8904
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