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In vitro mesenchymal stem cell culture using calcium phosphate glass scaffold
DC Field | Value | Language |
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dc.contributor.author | 김경남 | - |
dc.contributor.author | 김광만 | - |
dc.contributor.author | 김민철 | - |
dc.contributor.author | 김종관 | - |
dc.contributor.author | 김진 | - |
dc.contributor.author | 유주경 | - |
dc.contributor.author | 최성호 | - |
dc.date.accessioned | 2015-08-26T16:37:57Z | - |
dc.date.available | 2015-08-26T16:37:57Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 1013-9826 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/114821 | - |
dc.description.abstract | The purpose of this study was to evaluate the cell affinity of calcium phosphate glass scaffold in the system of CaO-CaF2-P2O5-MgO-ZnO, which is already reported that promoted the bone-like tissue formation in vitro and formed new bone in Sprague-Dawley rats. We prepared calcium phosphate glass saffolds with three-dimensionally interconnected pores of 200~500 µm. Commercial HA scaffold was employed as a control in this study. Bone marrow cells were collected from the healthy human donors and cultured within the prepared scaffolds. After 2, 4, 6, and 8 weeks, hMSCs/scaffold were fixed and stained with hematoxylin and eosin. hMSCs were continuously proliferated both in the experimental and control groups at every incubation period. The number of cells was higher in the experimental group than that of the control group, however, there was no significant difference (p>0.05). Extracellular matrices could be observed at the 2nd and 4th days in the experimental and control groups, respectively. The extracellular matrices were more abundant in the experimental group at all periods. The prepared calcium phosphate glass scaffolds are expected effective in bone tissue engineering. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 679~682 | - |
dc.relation.isPartOf | Key Engineering Materials | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Calcium Phosphate Glass | - |
dc.subject.MESH | Mesenchymal Stem Cell (MSC) | - |
dc.subject.MESH | Scaffold | - |
dc.title | In vitro mesenchymal stem cell culture using calcium phosphate glass scaffold | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Dental Engineering (치과생체재료공학) | - |
dc.contributor.googleauthor | J. Kim | - |
dc.contributor.googleauthor | J.K. Ryu | - |
dc.contributor.googleauthor | Yong Keun Lee | - |
dc.contributor.googleauthor | Racquel Z. LeGeros | - |
dc.contributor.googleauthor | Kwang Mahn Kim | - |
dc.contributor.googleauthor | Kyoung Nam Kim | - |
dc.contributor.googleauthor | Chong Kwan Kim | - |
dc.contributor.googleauthor | Seong Ho Choi | - |
dc.contributor.googleauthor | Yeon Ung Kim | - |
dc.contributor.googleauthor | Min Chul Kim | - |
dc.identifier.doi | 10.4028/www.scientific.net/KEM.284-286.679 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00292 | - |
dc.contributor.localId | A00312 | - |
dc.contributor.localId | A02512 | - |
dc.contributor.localId | A00479 | - |
dc.contributor.localId | A01009 | - |
dc.contributor.localId | A04081 | - |
dc.contributor.localId | A00914 | - |
dc.relation.journalcode | J01939 | - |
dc.identifier.pmid | 10.4028/www.scientific.net/KEM.284-286.679 | - |
dc.identifier.url | http://www.scientific.net/KEM.284-286.679 | - |
dc.subject.keyword | Calcium Phosphate Glass | - |
dc.subject.keyword | Mesenchymal Stem Cell (MSC) | - |
dc.subject.keyword | Scaffold | - |
dc.contributor.alternativeName | Kim, Kyoung Nam | - |
dc.contributor.alternativeName | Kim, Kwang Mahn | - |
dc.contributor.alternativeName | Kim, Min Chul | - |
dc.contributor.alternativeName | Kim, Chong Kwan | - |
dc.contributor.alternativeName | Kim, Jin | - |
dc.contributor.alternativeName | Ryu, Ju Kyoung | - |
dc.contributor.alternativeName | Choi, Seong Ho | - |
dc.contributor.affiliatedAuthor | Kim, Kyoung Nam | - |
dc.contributor.affiliatedAuthor | Kim, Kwang Mahn | - |
dc.contributor.affiliatedAuthor | Ryu, Ju Kyoung | - |
dc.contributor.affiliatedAuthor | Kim, Min Chul | - |
dc.contributor.affiliatedAuthor | Kim, Jin | - |
dc.contributor.affiliatedAuthor | Choi, Seong Ho | - |
dc.contributor.affiliatedAuthor | Kim, Chong Kwan | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 284~286 | - |
dc.citation.startPage | 679 | - |
dc.citation.endPage | 682 | - |
dc.identifier.bibliographicCitation | Key Engineering Materials, Vol.284~286 : 679-682, 2005 | - |
dc.identifier.rimsid | 38498 | - |
dc.type.rims | ART | - |
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