2 299

Cited 14 times in

Colorectal flat neoplasia

Authors
 W Ho Kim  ;  J Hoon Suh  ;  N Kyu Kim  ;  H Kim  ;  J Kyung Kang  ;  J Hee Jeong  ;  D Young Kim  ;  H Won Chung  ;  Y Han Paik  ;  S Kwan Shin  ;  T Il Kim 
Citation
 DIGESTIVE AND LIVER DISEASE, Vol.35(3) : 165-171, 2003 
Journal Title
 DIGESTIVE AND LIVER DISEASE 
ISSN
 1590-8658 
Issue Date
2003
MeSH
Adenocarcinoma/pathology* ; Adenocarcinoma/surgery ; Adenoma/pathology* ; Adenoma/surgery ; Adult ; Aged ; Colonoscopy ; Colorectal Neoplasms/pathology* ; Colorectal Neoplasms/surgery ; Female ; Humans ; Male ; Middle Aged ; Rectum/pathology ; Risk Factors
Keywords
Colorectal cancer ; Flat adenoma
Abstract
Background and aims. An attempt has been made to evaluate the clinicopathological characteristics of flat colorectal neoplastic lesions, and analyse the factors associated with the malignancy. Patients and methods. A total of 115 flat neoplastic lesions, ≥5 mm in size, diagnosed in 87 patients by colonoscopy, were investigated. Results. The rectum was the most common location. Almost half (49.6%) of the flat neoplasms were small (5–10 mm), 27.8% were 11–20 mm and the remainder (22.6%) larger than 20 mm. The surface was smooth in 55.7%, granular in 20.0% and nodular in 24.3%. Histologically, the flat lesions were tubular, tubulovillous and villous adenomas in 69.6%, 20.9% and 5.2%, respectively. Five lesions (4.3%) were composed of carcinomas without adenoma. High-grade dysplasia, intramucosal carcinoma and invasive carcinoma were diagnosed in 9.6%, 7.8% and 6.1% of all flat neoplasms, respectively. Univariate analysis demonstrated that the location, size, surface pattern and histologic type of the flat lesions were factors associated with malignancy. However, in multivariate analysis, the size of the flat lesions was the only significant risk factor for malignant transformation. Conclusions. Flat neoplastic lesions of the colorectum have a relatively high rate of malignancy, and size is the most important factor associated with malignancy.
Full Text
http://www.sciencedirect.com/science/article/pii/S1590865803000240
DOI
10.1016/S1590-8658(03)00024-0
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Kim, Do Young(김도영)
Kim, Won Ho(김원호) ORCID logo https://orcid.org/0000-0002-5682-9972
Kim, Tae Il(김태일) ORCID logo https://orcid.org/0000-0003-4807-890X
Kim, Ho Keun(김호근)
Paik, Yong Han(백용한)
Suh, Jeong Hoon(서정훈)
Shin, Sung Kwan(신성관) ORCID logo https://orcid.org/0000-0001-5466-1400
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/114513
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse