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Solitary plasmacytoma of the mandible in a renal transplant recipient

Authors
 J.H. Yoon  ;  J.I. Yook  ;  J. Kim  ;  W.I. Yang  ;  I.H. Cha  ;  H.J. Kim 
Citation
 INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, Vol.32(6) : 664-666, 2003 
Journal Title
 INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY 
ISSN
 0901-5027 
Issue Date
2003
MeSH
Adolescent ; Epstein-Barr Virus Infections/etiology ; Herpesvirus 4, Human/genetics ; Herpesvirus 4, Human/isolation & purification ; Humans ; Immunosuppressive Agents/adverse effects ; In Situ Hybridization ; Kidney Transplantation/adverse effects* ; Male ; Mandibular Neoplasms/etiology* ; Mandibular Neoplasms/pathology ; Mandibular Neoplasms/radiotherapy ; Mandibular Neoplasms/virology* ; Plasmacytoma/etiology* ; Plasmacytoma/pathology ; Plasmacytoma/radiotherapy ; Plasmacytoma/virology*
Keywords
plasmacytoma ; renal transplantation ; Epstein–Barr virus ; mandible.
Abstract
A solitary plasmacytoma occurring in the mandible of a 15-year-old Korean male 6 years after renal transplantation is reported. The tumour presented as a hyperplastic gingival overgrowth in the right madibular molar area. Histology and immunohistochemistry revealed plasmacytoma and monoclonality of the kappa chain and IgG. In situ hybridization for Epstein–Barr virus encoded RNA (EBER) showed positive signals in the tumour cells. The tumour regressed after reducing the immunosuppressive agents with concurrent radiotherapy. The patient remains in a stable condition with normal renal functions after 7 years without recurrence. This case confirms that Epstein–Barr virus associated B-lymphoproliferative disorders are still a major complication of immunosuppression.
Full Text
http://www.sciencedirect.com/science/article/pii/S0901502702904169
DOI
10.1054/ijom.2002.0416
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral and Maxillofacial Surgery (구강악안면외과학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Oral Pathology (구강병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jin(김진)
Yang, Woo Ick(양우익) ORCID logo https://orcid.org/0000-0002-6084-5019
Yook, Jong In(육종인) ORCID logo https://orcid.org/0000-0002-7318-6112
Cha, In Ho(차인호) ORCID logo https://orcid.org/0000-0001-8259-2190
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/114485
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