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전신성 홍반성 루푸스 환자에서 발작의 예측인자

Other Titles
 Predictive Factors for Seizure Attack in Patients with Systemic Lupus Erythematosus 
Authors
 박민찬  ;  박용범  ;  이수곤  ;  홍태원  ;  김철식  ;  김현욱 
Citation
 Journal of the Korean Rheumatism Association (대한류마티스학회지), Vol.10(4) : 351-357, 2003 
Journal Title
 Journal of the Korean Rheumatism Association (대한류마티스학회지) 
ISSN
 1226-8070 
Issue Date
2003
MeSH
Systemic lupus erythematosus ; Seizure ; Predictive factor ; Damage index ; Anticardiolipin antibody
Keywords
Systemic lupus erythematosus ; Seizure ; Predictive factor ; Damage index ; Anticardiolipin antibody
Abstract
Objective: This study was designed to identify the risk factors associated with seizure attack in patients with systemic lupus erythematosus (SLE) and to propose the usefulness of them as predictive factors for seizure attack. Methods: One hundred patients with SLE were included in this study. Twenty-five of these patients had seizure attacks during the course of their disease and age-, sex-matched 75 patients who did not have seizure were control group. We compared clinical manifestations and laboratory findings between the two groups. Seizures not related to SLE were excluded. Results: Risk factors associated with seizure attack in SLE were high damage index at initial presentation and the presence of anticardiolipin antibody IgG regardless of its titer. Underlying illness other than SLE, duration of SLE, presence of previous organic brain abnormality, SLEDAI at initial presentation, clinical manifestations of SLE, laboratory findings (including hematologic, immunologic parameters and known laboratory activity indices) and medications before seizure attack were not significantly associated with seizure attack. Recurred seizure was not associated with any of these factors. Conclusion: High damage index at initial presentation and the presence of anticardiolipin antibody IgG were associated with seizure attacks in patients with SLE. These factors may be used as predictive factor for seizure attack in SLE.
Files in This Item:
T200306795.pdf Download
DOI
OAK-2003-01317
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Min Chan(박민찬) ORCID logo https://orcid.org/0000-0003-1189-7637
Park, Yong Beom(박용범)
Lee, Soo Kon(이수곤)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/114477
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