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Central Nω-nitro-L-arginine Methyl Ester Does not Influence Lithium-induced c-Fos and Conditioned Taste Aversion
DC Field | Value | Language |
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dc.contributor.author | 김동구 | - |
dc.date.accessioned | 2015-07-15T17:07:00Z | - |
dc.date.available | 2015-07-15T17:07:00Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/114259 | - |
dc.description.abstract | LiCl at doses sufficient to induce conditioned taste aversion (CTA) causes c-Fos expression in the brain regions implicated in CTA formation. It has been reported that nitric oxide (NO) may play a role in CTA learning and LiCl increases both the synthesis and activity of NO synthase (NOS) in the brain. In this study, we examined the effect of central Nω-nitro-L-arginine methyl ester (L-NAME) on the brain c-Fos expression and CTA learning induced by lithium in rats. In the results, intracerebroventricular L-NAME given prior to lithium did not change either the lithium-induced CTA or c-Fos in the relevant brain regions. This suggests that the brain NO system may not be involved in the neuronal activation during lithium-induced CTA formation. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Conditioned taste aversion | - |
dc.subject.MESH | lithium chloride | - |
dc.subject.MESH | c-Fos | - |
dc.subject.MESH | nitric oxide | - |
dc.subject.MESH | rat | - |
dc.subject.MESH | intracerebroventricular injection | - |
dc.title | Central Nω-nitro-L-arginine Methyl Ester Does not Influence Lithium-induced c-Fos and Conditioned Taste Aversion | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pharmacology (약리학) | - |
dc.contributor.googleauthor | Jeong Won Jahng | - |
dc.contributor.googleauthor | Si Ho Choi | - |
dc.contributor.googleauthor | Thomas A. Houpt | - |
dc.contributor.googleauthor | Dong Goo Kim | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00396 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.subject.keyword | Conditioned taste aversion | - |
dc.subject.keyword | lithium chloride | - |
dc.subject.keyword | c-Fos | - |
dc.subject.keyword | nitric oxide | - |
dc.subject.keyword | rat | - |
dc.subject.keyword | intracerebroventricular injection | - |
dc.contributor.alternativeName | Kim, Dong Goo | - |
dc.contributor.affiliatedAuthor | Kim, Dong Goo | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 44 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 869 | - |
dc.citation.endPage | 874 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.44(5) : 869-874, 2003 | - |
dc.identifier.rimsid | 41870 | - |
dc.type.rims | ART | - |
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