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간편형 전립선특이항원검사 키트®의 유용성

Other Titles
 Usefulness of Rapid PSA Kit® 
Authors
 조진선  ;  최의열  ;  정병수  ;  홍창희  ;  이두진  ;  박상열 
Citation
 KOREAN JOURNAL OF UROLOGY, Vol.44(1) : 6-11, 2003 
Journal Title
KOREAN JOURNAL OF UROLOGY(대한비뇨기과학회지)
ISSN
 0494-4747 
Issue Date
2003
MeSH
Prostate-specific antigen ; Prostate cancer screening ; Rapid PSA kit
Keywords
Prostate-specific antigen ; Prostate cancer screening ; Rapid PSA kit
Abstract
Purpose: The incidence rate of prostate cancer has increased remarkably in Korea. The serum prostate specific antigen (PSA) value has been used for screening, although its clinical significance in prostate cancer screening is still inconclusive. However, if the measurement time was short and the cost was low, such an assay kit should be sufficient for prostate cancer screening. Materials and Methods: We developed pared monoclonal antibodies against PSA which could be used in assay kits for PSA. The Rapid PSA Kit used an immunochromatographic method to qualitatively judge a positive or negative result. Serum specimens from 78 men with benign prostate hyperplasia or prostate cancer were tested using the kit. Results: The sensitivity of the kit was determined to be 4ng/ml. 33 samples had a value of greater than 5ng/ml, so were considered positive. 5 samples had values between 4ng/ml and 5ng/ml, of which 3 were positive. The other 40 samples had values less than 4ng/ml, and 11 of these were judged positive. These results indicated that the sensitivity and specificity of the Rapid PSA Kit were 94.7 and 72.5%, respectively. Conclusions: Tests using the Rapid PSA Kit can be easily performed at outpatient clinics or elsewhere. This kit is useful in the initial screening of prostate cancer as the results can be obtained within 15 minutes and the cost is lower than with ordinary serum PSA tests.
Files in This Item:
T200305201.pdf Download
DOI
OAK-2003-00881
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Hong, Chang Hee(홍창희) ORCID logo https://orcid.org/0000-0002-0946-7702
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/114041
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