207 554

Cited 0 times in

Significance of chronic epilepsy in glial tumors

Authors
 Jung Yong Ah  ;  Ok-Joon Kim  ;  Byung-In Lee  ;  Sang Sup Chung  ;  Joong Uhn Choi  ;  Kyu Sung Lee 
Citation
 Journal of Korean Neurosurgical Society (대한신경외과학회지), Vol.34(3) : 192-196, 2003 
Journal Title
Journal of Korean Neurosurgical Society(대한신경외과학회지)
ISSN
 1225-8245 
Issue Date
2003
MeSH
Brain neoplasms ; Glioma ; Epilepsy
Keywords
Brain neoplasms ; Glioma ; Epilepsy
Abstract
Objective:The aim of this study is to compare the frequency of postoperative epilepsies of patients with chronic as opposed to recent onset epilepsy due to glial tumors in the frontal or temporal lobe with the hypothesis that patients with chronic epilepsy do worse.

Methods : We compared the clinical and diagnostic characteristics of the patients(n=73) who had seizures preoperatively to those of the patients(n=153) who did not. Among those who have had seizures preoperatively, we compared those(n=32, chronic seizure group) who had seizures a year or more prior to surgery to those(n=41, acute seizure group) who had seizures within a year prior to surgery.

Results : Among the various factors, the frequency of benign pathology and favorable neurological state were higher in seizure group than in non-seizure group(p<0.05). Complex partial seizure and low-grade tumors were frequent in chronic seizure group, whereas simple partial seizure and high-grade tumors were frequent in acute seizure group. Seizure-free rate was significantly higher in acute seizure group than in chronic one(p<0.05). Also, the difference of seizure control rate between surgical strategies were statistically significant(p<0.05).

Conclusion : This study indicates that preoperative seizure durations and frequencies have a close relationship with the frequency of postoperative epilepsy of glial tumors. A longer lapse may allow the formation of epileptogenic foci, leading to chronic epilepsy, and eventually having a negative effect on the prognosis of the patients. Factors including histopathological characteristics of the tumor, its location, seizure duration/frequency, and semiology should be taken account of deciding on surgical strategies.
Files in This Item:
T200304936.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Ahn, Jung Yong(안정용)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/113975
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links