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대장 직장에서 점액성 선암의 임상적 특징

Other Titles
 Clinicopathologic Characteristics of Colorectal Mucinous Carcinoma 
Authors
 이강영  ;  손승국  ;  허정욱  ;  민진식  ;  김남규  ;  이창목 
Citation
 JOURNAL OF THE KOREAN SURGICAL SOCIETY, Vol.64(2) : 140-143, 2003 
Journal Title
JOURNAL OF THE KOREAN SURGICAL SOCIETY (대한외과학회지)
ISSN
 1226-0053 
Issue Date
2003
MeSH
Colorectal cancer ; Mucinous carcinoma
Keywords
Colorectal cancer ; Mucinous carcinoma ; 대장암 ; 점액성 선암
Abstract
Purpose: The aim of this study was to assess the clinicopathological characteristics and prognosis of colorectal mucinous carcinomas.

Methods: 1,809 patients who underwent curative resection, between January 1989 and December 1999, for colorectal carcinomas, were enrolled in this study. Of these, 128 patients had more than 50% mucin secreting acini that could be classified as the mucinous type. These mucinous carcinoma patients were compared with 1,681 non-mucinous carcinoma patients, in order to evaluate differences in their clinicopathological characteristics, recurrence pattern and prognosis.

Results: The incidence of mucinous carcinomas was 7.1%. The mean age of the mucinous carcinoma patients was younger than the non-mucinous carcinoma patients (P=0.001). The mucinous carcinomas occurred in the right colon more frequently than non-mucinous carcinoma, and the size of the tumor was larger (P<0.001). There were no significant differences in the loco-regional and systemic recurrence rates, but the systemic recurrence pattern of the mucinous carcinomas was different from those of the non-mucinous carcinomas. With a mucinous carcinoma, the most common site for systemic recurrence was the peritoneal metastasis, whereas in a non-mucinous carcinoma, was the liver. There was no significant difference in the 5-year survival rate between the two groups.

Conclusion: In a mucinous carcinoma, the most common pattern of treatment failure was a peritoneal recurrence. The hepatic recurrence rate of the mucinous carcinomas was less than that of the non-mucinous carcinoma. Therefore, more aggressive diagnostic and therapeutic approaches, under the consideration of peritoneal recurrence in mucinous carcinomas, will be required.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Nam Kyu(김남규) ORCID logo https://orcid.org/0000-0003-0639-5632
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/113907
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