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CD30 (Ki-1)-positive large-cell cutaneous T-cell lymphoma with secondary xanthomatous changes after radiation therapy

Authors
 Han Gil Chung  ;  Yae Lee Chung  ;  Min-Geol Lee  ;  Jee Sook Hahn  ;  Chang Ok Suh  ;  Woo Ick Yang  ;  Jin Moon Kang 
Citation
 JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, Vol.48(Suppl.2) : 28-30, 2003 
Journal Title
 JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY 
ISSN
 0190-9622 
Issue Date
2003
MeSH
Aged ; Female ; Forehead ; Humans ; Ki-1 Antigen/analysis ; Lymphoma, T-Cell, Cutaneous/pathology* ; Lymphoma, T-Cell, Cutaneous/radiotherapy ; Skin Neoplasms/pathology* ; Skin Neoplasms/radiotherapy ; Xanthomatosis/etiology ; Xanthomatosis/pathology*
Keywords
12582380
Abstract
A 72-year-old woman with a large mass on her forehead was found to have primary cutaneous CD30-positive large T-cell lymphoma and was treated with radiation therapy. Five weeks after the completion of radiation therapy, a large, yellow plaque developed on the forehead. Histopathologic examination showed numerous xanthoma-like cells with clear and foamy cytoplasm that infiltrated the upper and mid dermis with no residual lymphoma. To our knowledge, this is the first report of xanthomatous change after radiation therapy for primary cutaneous CD30-positive large cell lymphoma. We believe that the xanthomatous change after radiation therapy probably was caused by lysis of radiosensitive lymphoma cells and histiocytic scavenging of lipid-membrane debris.
Full Text
http://www.sciencedirect.com/science/article/pii/S0190962202615270
DOI
10.1067/mjd.2003.123
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Suh, Chang Ok(서창옥)
Yang, Woo Ick(양우익) ORCID logo https://orcid.org/0000-0002-6084-5019
Lee, Min Geol(이민걸) ORCID logo https://orcid.org/0000-0001-7040-5335
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/113876
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