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Influence of Sex on Patients with Behcet's Disease in Korea

Authors
 DongSik Bang  ;  SangHo Oh  ;  SungNack Lee  ;  Eun-So Lee  ;  Kwang-Hoon Lee 
Citation
 JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.18(2) : 231-235, 2003 
Journal Title
 JOURNAL OF KOREAN MEDICAL SCIENCE 
ISSN
 1011-8934 
Issue Date
2003
MeSH
Adolescent ; Adult ; Age of Onset ; Aged ; Behcet Syndrome/epidemiology ; Behcet Syndrome/physiopathology* ; Child ; Female ; Humans ; Korea ; Male ; Middle Aged ; Retrospective Studies ; Sex Characteristics*
Keywords
Behcet Disease ; Sex ; Morbidity
Abstract
Behcet's disease (BD) is a multisystemic inflammatory disorder known as having a histopathological findings of vasculitis. The influence of sexual difference on BD is a well-known fact and there are several reports suggesting a more severe course of the disease among young males. The purpose of our study was to determine the effects of gender on the severity and clinical features of BD patients in Korea. The study included 1,901 patients with BD who fulfilled the criteria of International Study Group for Behcet's Disease or corresponded to the complete or incomplete type for the revised criteria of Behcet's Disease Research Committee of Japan. BD in Korea showed a female predominance (M:F=0.61:1). The skin lesions were observed in 79.9% of patients, of which 77.6% had erythema nodosum-like lesion, which was more frequent in females. The ocular lesions were more common in males showing a higher frequency of uveitis. Ocular and vascular symptoms as clinical features with severe complications or mortality were more frequent in males than in females. The mean age at the onset of patients with the worst prognosis such as ocular, gastrointestinal, neurologic, and vascular involvements was significantly younger in male than in female patients (p<0.05). In conclusion, this study elucidated the influences of sexual difference on BD in Korea.
Files in This Item:
T200304527.pdf Download
DOI
10.3346/jkms.2003.18.2.231
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Bang, Dong Sik(방동식)
Lee, Kwang Hoon(이광훈)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/113871
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