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제한형 전신피부경화증에 병발한 현미경적 다발혈관염

Other Titles
 A case of microscopic polyangiitis combined with limited systemic sclerosis. 
Authors
 이원기  ;  박용범  ;  이수곤  ;  정현주 
Citation
 Journal of the Korean Rheumatism Association (대한류마티스학회지), Vol.10(3) : 310-314, 2003 
Journal Title
 Journal of the Korean Rheumatism Association (대한류마티스학회지) 
ISSN
 1226-8070 
Issue Date
2003
Keywords
Systemic sclerosis ; Microscopic polyangiitis
Abstract
We report a case of microscopic polyangiitis in a 52-year-old woman combined with systemic sclerosis. She was diagnosed as having limited systemic sclerosis based on symmetric skin thickening of fingers and distal arms, loss of substance from the finger pad, and bibasilar pulmonary fibrosis. Laboratory investigations showed positive antitopoisomerase I antibody. Subsequent evaluation revealed proteinuria and hematuria. Her serum creatinine concentration was elevated with detoriorated glomerular filtration. Serum antimyeloperoxidase antibody was strongly positive. A sural nerve biopsy revealed axonopathy due to early manifestations of vasculitis. Percutaneous renal biopsy showed focal necrotizing glomerulonephritis. Her renal function recovered with immunosuppressive therapy with high dose prednisolone and oral cyclophosphamide.
Files in This Item:
T200304504.pdf Download
DOI
OAK-2003-00703
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Park, Yong Beom(박용범)
Lee, Soo Kon(이수곤)
Jeong, Hyeon Joo(정현주) ORCID logo https://orcid.org/0000-0002-9695-1227
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/113863
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