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여성 급성단순성방광염의 원인균에 따른 항생제감수성의 다기관 임상조사

Other Titles
 A Multicenter Study of Antimicrobial Susceptibility of Uropathogens Causing Acute Uncomplicated Cystitis in Woman 
Authors
 이승주  ;  조용현  ;  이춘용  ;  김원재  ;  김철성  ;  류수방  ;  조인래  ;  심봉석  ;  임정식  ;  최영득  ;  김민의  ;  이상은  ;  이상돈  ;  정세일  ;  이정구  ;  김법완 
Citation
 KOREAN JOURNAL OF UROLOGY, Vol.44(7) : 697-701, 2003 
Journal Title
KOREAN JOURNAL OF UROLOGY(대한비뇨기과학회지)
ISSN
 0494-4747 
Issue Date
2003
MeSH
Woman ; Cystitis ; Disease susceptibility
Keywords
Woman ; Cystitis ; Disease susceptibility
Abstract
PURPOSE: Worldwide data shows that there is an increasing resistance among urinary tract pathogens to the first-line antimicrobial agents used in domestic areas. The objective of this study was to obtain data on the susceptibility patterns of the pathogens responsible for acute uncomplicated cystitis to currently used antimicrobial agents. MATERIALS AND METHODS: This study was carried out with the participation of fifteen hospitals in South Korea. A total of 239 isolates were obtained from female outpatients with acute uncomplicated cystitis. The antimicrobial susceptibilities to ampicillin, ampicillin/sulbactam, ciprofloxacin, gentamicin, trimethoprim/sulfamethoxazole (TMP/SMX) and tobramycin were determined by Vitek antimicrobial susceptibility test systems. RESULTS: The most prevalent causative organism was Escherichia coli (79.9%), followed by coagulase negative Staphylococcus (4.2%), and a combination of other species of Enterobacteriaceae (8.2%). The mean rates of susceptibility were 35.5, 45.0, 85.7, 81.5, 62.1 and 85.3% to ampicillin, ampicillin/sulbactam, ciprofloxacin, gentamicin, TMP/ SMX and tobramycin, respectively. No significant differences were detected in the resistance rates between the results from 4 regional groups. CONCLUSIONS: The high prevalence of resistance to ampicillin, ampicillin/sulbactam, and TMP/SMX suggest these drugs would not provide adequate initial therapy, and therapies other than TMP/SMX may need to be considered. The relatively high prevalence of resistance to ciprofloxacin, compared with other countries, also requires on going surveillance to identify further changes among urinary tract isolates.
Files in This Item:
T200304307.pdf Download
DOI
OAK-2003-00652
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Choi, Young Deuk(최영득) ORCID logo https://orcid.org/0000-0002-8545-5797
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/113812
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