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Behçet's Disease: The First Mongolian Case in Literature Showing HLA B51, MICA Gene Type *5/*6

Authors
 Yae Lee Chung  ;  Dong Sik Bang  ;  Kyung Sook Park  ;  Jee Won Mok  ;  Sung Nack Lee  ;  Eun So Lee 
Citation
 YONSEI MEDICAL JOURNAL, Vol.44(5) : 935-938, 2003 
Journal Title
 YONSEI MEDICAL JOURNAL 
ISSN
 0513-5796 
Issue Date
2003
MeSH
• Adult ; Alleles ; Behcet Syndrome/genetics* ; Behcet Syndrome/immunology ; Genotype ; HLA-B Antigens/genetics* ; HLA-B51 Antigen ; Histocompatibility Antigens Class I/genetics* ; Humans ; Male
Keywords
Behcet's disease ; mongolian ; HLA B51 ; MICA genotype
Abstract
Behçet's disease is a chronic multi-systemic disease of unknown origin that includes mucocutaneous, ocular, cardiac, vascular, renal, gastrointestinal, neurologic and cutaneous involvement. The disease is spread throughout the world, but it is most prevalent in the eastern Mediterranean region-along the Silk Road-, and in Japan, China, and Korea. Recently, we treated a Mongolian patient who had complete-type Behçet's disease. As far as we know, this case is the first report of a Mongolian with Behçet's disease in the English literature. HLA typing in this patient revealed A2, A24; B51, B35; Cw4, Cw7; DR9, DR11. Study of the MICA genetype showed *5, *6 positive. Our data provided adequate evidence, from an epidemiological aspect, to support the belief that Behçet's disease is most prevalent along the old Silk Road.
Files in This Item:
T200304082.pdf Download
DOI
10.3349/ymj.2003.44.5.935
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Bang, Dong Sik(방동식)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/113750
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