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두부 양전자 방출 단층촬영으로 확인된 신경정신 루푸스 1예

Other Titles
 Neuropsychiatric Lupus Diagnosed by Brain PET -A Case Report- 
Authors
 정상윤  ;  문진욱  ;  이수곤  ;  윤미진  ;  박용범  ;  박민찬 
Citation
 Journal of the Korean Rheumatism Association (대한류마티스학회지), Vol.10(3) : 325-330, 2003 
Journal Title
 Journal of the Korean Rheumatism Association (대한류마티스학회지) 
ISSN
 1226-8070 
Issue Date
2003
Keywords
Systemic lupus erythematosus ; Neuropsychiatric lupus ; Magnetic resornance imaging (MRI) ; F-18-fluoro-2-deoxy-D-glucose positron emission tomography (18FDG-PET)
Abstract
Neuropsychiatric lupus is a complication of systemic lupus erythematosus (SLE) characterized by profound metabolic alteration including impaired blood flow, ischemia, decreased aerobic metabolism and progressive neuronal loss of central nervous system. Because of the lack of useful diagnostic methods, it`s diagnosis and management is difficult. Recently, F-18-fluoro-2-deoxy-D-glucose positron emission tomography (18FDG-PET) is considered to be a sensitive and reliable method for evaluating SLE patients with neuropsychiatric involvement as compared with brain computed tomography (CT) or magnetic resornance imaging (MRI). In SLE patient having mild or severe neuropsychiatric manifestations, 18FDG-PET shows hypo- or hypermetabolism by different glucose utilization in brain tissue. We experienced a 23-year-old woman with SLE who presented with seizure and loss of consciousness. Initially, brain MRI finding was negative, but brain 18FDG-PET revealed significant hypometabolism in the cerebral hemisphere at active stage of disease and complete resolution of metabolic abnormalities after treatment. Herein, we report a case of neuropsychiatric lupus diagnosed by brain 18FDG-PET.
Files in This Item:
T200303804.pdf Download
DOI
OAK-2003-00506
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Yong Beom(박용범)
Lee, Soo Kon(이수곤)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/113666
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