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Diversity of TEM-52 extended-spectrum β-lactamase-producing non-typhoidal Salmonella isolates in Korea

DC FieldValueLanguage
dc.contributor.author염종화-
dc.contributor.author용동은-
dc.contributor.author이경원-
dc.date.accessioned2015-07-15T16:43:17Z-
dc.date.available2015-07-15T16:43:17Z-
dc.date.issued2003-
dc.identifier.issn0305-7453-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/113465-
dc.description.abstractOBJECTIVES: Extended-spectrum beta-lactamase (ESBL)-producing non-typhoidal Salmonella (NTS) isolates in Korea were characterized. PATIENTS AND METHODS: Five isolates of ESBL-producing NTS were isolated from stool specimens of three infants and two adults with diarrhoea. Two infants acquired the infection in the community, and three other infections were hospital acquired. RESULTS: The isolates were one each of serovars Saintpaul, Stanley and Agona, and two Enteritidis. Cell sonicates of the isolates hydrolysed cefotaxime more efficiently than ceftazidime, and had beta-lactamase bands of approximate isoelectric points 6.0 and 7.4. Sequencing revealed that the beta-lactamases were TEM-52 and an OXA type. The blaOXA gene was located on a class 1 integron. Cefotaxime resistance, associated with TEM-52, was transferred by conjugation. Identical pulsed-field gel electrophoresis patterns of XbaI-digested genomic DNA were observed in initially beta-lactam-susceptible serovar Agona isolates and subsequent ESBL-producing isolates from an infant, and in two isolates of serovar Enteritidis from two different patients. CONCLUSIONS: This study suggests that TEM-52-producing NTS is spreading both clonally and horizontally in Korea.-
dc.description.statementOfResponsibilityopen-
dc.format.extent493~496-
dc.relation.isPartOfJOURNAL OF ANTIMICROBIAL CHEMOTHERAPY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHenteritis-
dc.subject.MESHclass 1 integron-
dc.subject.MESHOXA-type β-lactamase-
dc.titleDiversity of TEM-52 extended-spectrum β-lactamase-producing non-typhoidal Salmonella isolates in Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthorKyungwon Lee-
dc.contributor.googleauthorDongeun Yong-
dc.contributor.googleauthorYunsop Chong-
dc.contributor.googleauthorHo Hoon Kim-
dc.contributor.googleauthorJong Hwa Yum-
dc.identifier.doi10.1093/jac/dkg385-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02352-
dc.contributor.localIdA02423-
dc.contributor.localIdA02649-
dc.relation.journalcodeJ01237-
dc.identifier.eissn1460-2091-
dc.identifier.pmid10.1093/jac/dkg385-
dc.subject.keywordenteritis-
dc.subject.keywordclass 1 integron-
dc.subject.keywordOXA-type β-lactamase-
dc.contributor.alternativeNameYum, Jong Hwa-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.alternativeNameLee, Kyung Won-
dc.contributor.affiliatedAuthorYum, Jong Hwa-
dc.contributor.affiliatedAuthorYong, Dong Eun-
dc.contributor.affiliatedAuthorLee, Kyung Won-
dc.rights.accessRightsfree-
dc.citation.volume52-
dc.citation.number3-
dc.citation.startPage493-
dc.citation.endPage496-
dc.identifier.bibliographicCitationJOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, Vol.52(3) : 493-496, 2003-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
5. Research Institutes (연구소) > Research Institute of Bacterial Resistance (세균내성연구소) > 1. Journal Papers

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