키토올리고당과 자일리톨 및 아연이 포함된 구강청정제(마이센스액)의 구취감소, 치태형성 및 재부착 억제, 치은염 완화 효과에 대한 연구

Abstract

This study reports the effect of Chito-oligosaccharide, Xylitol and Zinc on reduction of dental plaque, gingivitis and halitosis. Chilo-oligosaccharide, extracted from Chitin, is being widely used in medical field for its antibacterial effect on broad spectrum of microorganism without adverse effect on human body. Xylitol inhibits metabolism of streptococcus mutans , the main microorganism causing dental caries, and facilitates remineralization of tooth surface. Zinc, main component of a typical hydrated compound, effectively eliminates volatile sulfur compound. Through 70 healthy, non-smoking men and women of age 20s without dental caries, periodontal disease, antibiotic administration, the effectiveness of the above agents were evaluated, and the following results were obtained. Mouthrinse used in this study is free of problems arising from other chemical bactericidals, such as Chlorhexidine. It inhibits formation of dental plaque through its antibacterial action against specific microorganisms that cause dental caries, periodontal disease, plaque formation and accumulation, moreover, with the antiinflammtory effect of chitooligosaccharide, prevention as well as treatment of periodontitis is expected. For wettability of chito-oligosaccharide, it remains intraorally for a relatively long time, and since it is drinkable, it is effective at posterior region of tongue as well as paratonsilar area. Through the action of zinc, it reduces halitiosis effectively. In particular, it is alcohol free, unlike other mouthrinse which contain alcohol as preservative. Therefore, it is expected to show high efficacy as a new generation of mouthrinse.