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Complete Resolution of Posttransplant Lymphoproliferative Disorder (Diffuse Large B-cell Lymphoma) with Reduction of Immunosuppressive Therapy

 Jee Sook Hahn  ;  Yu Seun Kim  ;  Han Jak Ryu  ;  Kiil Park  ;  Woo Ick Yang  ;  Jong Doo Lee 
 Yonsei Medical Journal, Vol.45(3) : 527-532, 2004 
Journal Title
 Yonsei Medical Journal 
Issue Date
Adult ; Graft Rejection/drug therapy* ; Humans ; Immunosuppressive Agents/administration & dosage* ; Kidney Transplantation* ; Korea ; Lymphoma, Large B-Cell, Diffuse/diagnostic imaging ; Lymphoma, Large B-Cell, Diffuse/drug therapy* ; Male ; Remission Induction ; Tomography, Emission-Computed ; Tomography, X-Ray Computed
PTLD ; immunosuppression ; reduction ; resolution
Posttransplant lymphoproliferative disorder (PTLD) is a serious complication of organ transplantation. PTLD is the disorder arising from the combined effects of Epstein-Barr virus associated lymphoid proliferation with the disruption of the normal immune control by the cytotoxic T cells. The treatment for PTLD is one of the most controversial topics in solid organ transplantation. It is well known that the initial management of PTLD is a reduction of immunosuppression. Early diagnosis and the early reduction in immunosuppression are essential even for monomorphic lymphoma. We report here on a case of the complete resolution of PTLD (diffuse large B cell lymphoma) which occurred after a drastic reduction of immunosuppression in a renal transplant recipient.
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1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Yu Seun(김유선) ORCID logo https://orcid.org/0000-0002-5105-1567
Park, Ki Il(박기일)
Yang, Woo Ick(양우익) ORCID logo https://orcid.org/0000-0002-6084-5019
Lee, Jong Doo(이종두)
Hahn, Jee Sook(한지숙)
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