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Bimatoprost가 시신경유두 및 망막혈류에 미치는 단기효과
DC Field | Value | Language |
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dc.contributor.author | 김찬윤 | - |
dc.contributor.author | 성공제 | - |
dc.date.accessioned | 2015-07-14T17:13:21Z | - |
dc.date.available | 2015-07-14T17:13:21Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 0378-6471 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/112449 | - |
dc.description.abstract | Purpose: To demonstrate the effects of bimatoprost on the optic nerve head (ONH) and peripapillary retinal blood flow. Methods: Sixteen healthy volunteers were recruited. In a randomized, double-blind design, one eye received a drop of bimatoprost and the other eye a drop of placebo. ONH and peripapillary retinal blood flow parameters (flow, volume, velocity) were measured with HRF before, and at 1, 6 and 24 hours after eyedrops and blood pressure (BP), heart rate (HR), and intraocular pressure (IOP) were recorded. Results: The 16 subjects comprised 13 males and 3 females with a mean age of 27.3±2.4 years. IOP decreased significantly in the bimatoprost-treated eyes at 1, 6 and 24 hours after eyedrops (p<0.05). BP and HR were unchanged after bimatoprost eyedrops. The flow was significantly higher in the temporal peripapillary retina in the bimatoprost-treated eyes 1 hour after eyedrops and the velocity was also higher 6 hours after eyedrops at the same location. At the optic disc, there was a significant increase of the volume in the bimatoprost group 1 hour after eyedrops. There was no significant decrease of HRF parameters in the bimatoprost-treated eyes. Conclusions: These results suggest that bimatoprost does not have any adverse effect on ONH or peripapillary retinal blood flow. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1322~1329 | - |
dc.relation.isPartOf | JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Bimatoprost가 시신경유두 및 망막혈류에 미치는 단기효과 | - |
dc.title.alternative | The Short Term Effects of Bimatoprost on Optic Nerve Head and Peripapillary Retinal Blood Flow | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | 김선웅 | - |
dc.contributor.googleauthor | 김찬윤 | - |
dc.contributor.googleauthor | 성공제 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.relation.journalcode | J01838 | - |
dc.identifier.eissn | 2092-9374 | - |
dc.subject.keyword | Bimatoprost | - |
dc.subject.keyword | Ocular Blood flow | - |
dc.subject.keyword | Optic nerve head | - |
dc.subject.keyword | Peripapillary retina | - |
dc.contributor.alternativeName | Kim, Chan Yun | - |
dc.contributor.alternativeName | Seong, Gong Je | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 45 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1322 | - |
dc.citation.endPage | 1329 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY, Vol.45(8) : 1322-1329, 2004 | - |
dc.identifier.rimsid | 56181 | - |
dc.type.rims | ART | - |
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