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한국 소아 윌름스 종양의 역학 및 치료 성적

Other Titles
 Epidemiology and Clinical Outcomes of Childhood Wilms Tumor in Korea 
Authors
 서원석  ;  강임주  ;  구홍회  ;  국훈  ;  김순기  ;  김학기  ;  김황민  ;  김흥식  ;  박경덕  ;  박경배  ;  박상규  ;  박재선  ;  박준은  ;  박현진  ;  서종진  ;  성기웅  ;  신희영  ;  안효섭  ;  양창현  ;  유건희  ;  유경하  ;  유은선  ;  유철주  ;  이광철  ;  이건수  ;  이순용  ;  이영호  ;  임영탁  ;  장필상  ;  정낙균  ;  정대철  ;  정혜림  ;  조동완  ;  조빈  ;  최용묵  ;  하정옥  ;  황평한  ;  황태주 
Citation
 Korean Journal of Pediatric Hematology-Oncology (대한소아혈액종양학회지), Vol.11(2) : 164-170, 2004 
Journal Title
 Korean Journal of Pediatric Hematology-Oncology (대한소아혈액종양학회지) 
ISSN
 1225-6978 
Issue Date
2004
Keywords
Wilms tumor ; Epidemiology ; Survival rate ; Relapse rate
Abstract
Purpose: Wilms tumor is the most common malignant renal tumor in children. We investigated the epidemiology, clinical features and treatment outcome of the children with Wilms tumor in Korea during the recent 10 years. Methods: Two hundred forty six patients were enrolled between January 1991 and December 2000 from 26 major hospitals in Korea. The data regarding the clinical features including sex, age, pathologic type, prognostic factor and treatment outcome of patients were analyzed retrospectively by review of patient's medical records. Kaplan-Meier survival curves were constructed, The differences between groups were analyzed by log-rank test. Results: There were 130 males and 116 females. The incidence between the age of 1~4 years was the highest with 66.2%. The annual incidence rate per 1,000,000 population varied from 1.9 to 2.1. The 10 years overall survival rate according to sex, clinical stage, pathologic type and relapse were as follows: 88.6% in male, 90.9% in female, 100% in stage I, 94.7% in stage II, 92.1% in stage III, 63.4% in stage IV, 85.7% in stage V, 95.3% in favorable histology, 64.1% in unfavorable histology, 94.8% in non-relapse, and 40.9% in relapse. The relapse rate was 12%. The 10 years overall survival rate of 246 patients were 89.1%. Conclusion: Our results could provide the most recent and important clinical information on Wilms tumor of children in Korea.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Lyu, Chuhl Joo(유철주) ORCID logo https://orcid.org/0000-0001-7124-7818
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/112395
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