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심장판막수술을 받는 성인환자에서 시행한 변형초여과법의 혈역학적 효과

Other Titles
 Hemodynamic Effects of Modified Ultrafiltration (MUF) in Adult Patients Undergoing Valvular Heart Surgery 
 이종화  ;  박욱  ;  곽영란  ;  송종욱  ;  이용경  ;  김지영  ;  배선준 
 KOREAN JOURNAL OF ANESTHESIOLOGY, Vol.47(6) : 808-815, 2004 
Journal Title
Issue Date
modified ultrafiltration ; cardiopulmonary bypass ; hemodynamics ; valvular heart disease
Background: Modified ultrafiltration (MUF) has been demonstrated to have beneficial effects in children undergoing cardiac surgery with cardiopulmonary bypass (CPB). In adults, the hemodynamic effects of MUF are little known. The purpose of this investigation is to evaluate the hemodynamic effects of MUF in adult patients undergoing valvular heart surgery. Methods: 30 patients scheduled for elective mitral valvular surgery were randomized into either Ultrafiltration (U) or Control (C) group. In the U group, MUF was performed just after termination of CPB for 20 minutes, and not in the C group. Measurements of hemodynamic variables including right ventricular ejection fraction (RVEF) measured by thermodilution technique and hematocrit were performed before induction, just after termination of CPB, after completion of MUF and after sternal closure. Measurement after MUF in the C group was performed at 20 minutes after the termination of CPB. After transfer to ICU, same measurements were performed at postoperative 6 and 12 hrs. Results: After MUF, RVEF (P <0.05) and hematocrit (P < 0.01) increased in the U group, compared to the corresponding values measured just after termination of CPB. However, the variables were not statistically different between the two groups throughout the intraoperative procedures and during ICU stay. Conclusions: Conclusively, MUF was demonstrated to have the transient beneficial effect of improving the right heart function and hemoconcentration immediately after termination of CPB.
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1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Kwak, Young Lan(곽영란) ORCID logo https://orcid.org/0000-0002-2984-9927
Kim, Ji Young(김지영) ORCID logo https://orcid.org/0000-0001-5822-0338
Bai, Sun Joon(배선준) ORCID logo https://orcid.org/0000-0001-5027-3232
Lee, Yong Kyung(이용경)
Lee, Jong Wha(이종화)
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