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미세혈관 합병증이 없는 노인 당뇨병 환자에서 무증상의 죽상 경화증의 위험요인에 대한 분석

Other Titles
 Risk Factors for Asymptomatic Atherosclerosis in Elderly Diabetic Patients without Diabetic Microvascular Complications 
Authors
 박종숙  ;  남주영  ;  이현철  ;  김경래  ;  임승길  ;  차봉수  ;  안철우  ;  박진아  ;  조민호  ;  김똘미  ;  김철식 
Citation
 Korean Journal of Clinical Geriatrics (임상노인의학회지), Vol.5(2) : 208-215, 2004 
Journal Title
 Korean Journal of Clinical Geriatrics (임상노인의학회지) 
ISSN
 1229-6538 
Issue Date
2004
Keywords
Type 2 diabetes ; Atherosclerosis ; IMT (intima media thickness)
Abstract
Background: Diabetes Mellitus is a major independent risk factor for atherosclerosis. We have no information on the prevalence of asymptomatic atherosclerosis in diabetic patients before the onset of microvascular diseases. The aims of this study was to evaluate risk factors for the atherosclerosis in elderly type 2 diabetic patients without the microvascular diseases. Methods: We evaluated atherosclerotic change of carotid arteries in 60 elderly Korean type 2 diabetic patients who had neither atherosclerotic vascular diseases nor diabetic microvascular complications.When atherosclerotic change was defined as the mean intima-media thickness (IMT) of >1.0 mm and/or the presence of plaque lesion, 28.3% of patients had atherosclerosis of the carotid arteries. Results: Risk factors for the carotid atherosclerosis were age, low-density lipoprotein (LDL)-cholesterol, hypertension, and diabetes treatment. Age and LDL-cholesterol were associated with mean IMT. Fasting plasma glucose, glycosylated hemoglobin (HbA1c), and known diabetes duration remained unassociated with any parameters of asymptomatic atherosclerosis of the carotid arteries. Conclusion: Glycemic control is unrelated with asymptomatic atherosclerosis in elderly type 2 diabetic patients without diabetic microvascular complications. Conventional risk factors and diabetes treatment are independently associated with atherosclerosis of the carotid arteries in these patients.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Rae(김경래)
Kim, Dol Mi(김똘미)
Kim, Chul Sik(김철식)
Nam, Ju Young(남주영)
Park, Jong Suk(박종숙) ORCID logo https://orcid.org/0000-0002-5385-1373
Park, Jina(박진아)
Ahn, Chul Woo(안철우) ORCID logo https://orcid.org/0000-0003-3733-7486
Lee, Hyun Chul(이현철)
Lim, Sung Kil(임승길)
Cha, Bong Soo(차봉수) ORCID logo https://orcid.org/0000-0003-0542-2854
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/111964
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