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Other Titles
 Lyme Disease 
Authors
 이민걸  ;  조영훈 
Citation
 JOURNAL OF THE KOREAN MEDICAL ASSOCIATION , Vol.47(11) : 1063-1069, 2004 
Journal Title
 JOURNAL OF THE KOREAN MEDICAL ASSOCIATION 
ISSN
 1975-8456 
Issue Date
2004
Keywords
Borrelia burgdorferi ; Ixodes ; Erythema migrans ; Borrelia lymphocytoma ; Acrodermatitis chronica atrophicans ; 참진드기 ; 유주성 홍반 ; borrelial 림프구종 ; 만성 위축성 선단피부염
Abstract
Lyme disease is a vector-borne infection primarily transmitted by Ixodes ticks and is caused by at least three different but closely related species of borrelia. Although it is the most common arthropod-borne disease in the U.S. and Europe, reports of the clinical cases have been relatively rare in Korea. The disease may affect different organs, such as nervous system, joints, heart or eyes, and the clinical pictures include meningitis, cranial neuritis, arthritis, temporary atrioventricular block, and conjunctivitis. The cutaneous manifestations are erythema(chronicum) migrans, borrelial lymphocytoma, and acrodermatitis chronica atrophicans. Early localized infection occurs a few weeks after a tick bite, and erythema migrans is a classic cutaneous manifestation at this stage of infection. Several weeks later, early disseminated infection occurs with bacterial dissemination. Multiple erythema migrans-like skin lesions, neuroborreliosis, arthritis, and carditis can develop. Without treatment, the disease can progress to late or chronic infection, and then acrodermatitis chronica atrophicans may develop in addition to the systemic manifestations. The disease can be diagnosed with serologic tests such as indirect immunofluorescence test or ELISA. The recommended treatment is oral doxycycline or amoxicillin, and the treatment period is variable depending on the organ involved and the duration of the disease. A vaccine for the Lyme disease is approved for adults and commercially available in the Unites States. However, protection from tick bites by the use of protective clothing in risk areas and body inspection and removal of any attached ticks as soon as possible are the most important prophylactic methods. Chemoprophylaxis after a tick bite is also available.
Files in This Item:
T200400183.pdf Download
DOI
10.5124/jkma.2004.47.11.1063
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Min Geol(이민걸) ORCID logo https://orcid.org/0000-0001-7040-5335
Cho, Young Hun(조영훈)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/111938
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