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동종조혈모세포이식술 시술기관의 진료량이 이식후 생존율에 미치는 영향

Other Titles
 Association of Hospital Procedure Volume with Post-Transplant Survival for Allogeneic BoneMarrow Transplantation 
Authors
 박춘선  ;  문희경  ;  조우현  ;  민유홍  ;  강혜영 
Citation
 Journal of Preventive Medicine and Public Health, Vol.37(1) : 26-36, 2004 
Journal Title
 Journal of Preventive Medicine and Public Health 
ISSN
 0254-5985 
Issue Date
2004
Keywords
Volume-outcome relationship ; Allogeneic bone marrow transplantation ; Hospital procedure volume ; Post-transplant survival
Abstract
Objective : To examine the association between hospital procedure volume and treatment outcomes following allogeneic bone marrow transplantation (allo-BMT). Methods : Out of 1,050 patients who received allo-BMTs between 1998 and 2000 in 21 Korean hospitals, 752 with first allo-BMT and complete data were included in this study. Study subjects were divided into the following three groups according to cumulative hospital experience of all-BMTs during the study period: low (<30 cases), medium (30-49) and high (≥50 cases) volume. Patient outcome was defined as early survival at day 100 and one-year survival. Multiple logistic regression analyses were performed to examine the association between hospital experience and survival at day 100 and one year. Results : When the low volume group was defined as the reference group, the adjusted relative risks (RR) of survival at day 100 for the high volume group were 2.46(95% CI, 1.13-5.36) for all patients, 2.61(1.04-6.57) for those with leukemia, and 2.20(0.47-10.32) for those with aplastic anemia. For one-year survival, adjusted RR for the high volume group were 2.52(1.40-4.51) for all patients, 1.99 (1.01-3.93) for leukemia, and 6.50(1.57-26.80) for aplastic anemia. None of the RR for the medium volume group was statistically significant. Patient factors showing significant relationship with survival were donor-recipient relation, human leukocyte antigen matching status, time from diagnosis to transplant, and disease stage. Conclusions : The study results suggest that the cumulative experience of hospitals in providing allo-BMT is positively associated with patient survival.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers
Yonsei Authors
Min, Yoo Hong(민유홍) ORCID logo https://orcid.org/0000-0001-8542-9583
Cho, Woo Hyun(조우현)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/111924
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