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고농도 Sevoflurane을 이용한 폐활량 흡입마취유도시사전 산소 및 대기 호흡군 간의 호흡 양상의 차이

Other Titles
 Effects of Normocapneic Preoxygenation and Air Breathing during Vital Capacity Inhalation Induction with Sevoflurane on the Ventilation 
Authors
 구본녀  ;  길혜금  ;  전덕희  ;  김원옥 
Citation
 KOREAN JOURNAL OF ANESTHESIOLOGY, Vol.47(2) : 167-173, 2004 
Journal Title
KOREAN JOURNAL OF ANESTHESIOLOGY(대한마취과학회지)
ISSN
 2005-6419 
Issue Date
2004
Keywords
apnea ; breath holding ; preoxygenation ; sevoflurane ; vital capacity inhalation induction
Abstract
BACKGROUND: Sevoflurane has been used to provide an inhaled induction by using a vital capacity breath, which is fast and has few side effects. We compared the clinical effects of a vital capacity inhalation induction (VCII) with sevoflurane in patients of preoxygenation or air-breathing before anesthetic induction.

METHODS: After IRB approval, patients were randomly assigned to receive preoxygenation (O2 group, 70 patients) or air breathing (Air group, 70 patients) via SIBI (Single Breath Induction) connector™ before VCII with 8% sevoflurane in 75% N2O/O2 from primed circuit. The clinical characteristics were compared between two groups in respect to prolongation of breath holding after loss of consciousness (response to verbal command) and side effects (airway, hemodynamic, motor) during VCII.

RESULTS: O2 group showed lower incidence (60.0% vs. 87.1%, P < 0.05) and shorter duration (27.1 s vs. 36.4 s, P < 0.05) in prolongation of breath holding than Air group. Otherwise, there were no significant differences in clinical effects between two groups.

CONCLUSIONS: We found that preoxygenation reduces the incidence and duration of prolongation of breath holding during VCII with sevoflurane compared with air-ventilation before VCII. We suggest that the prolongation of breath holding might be related to Hering-Breuer response to maximal lung inflation during VCII.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Koo, Bon-Nyeo(구본녀) ORCID logo https://orcid.org/0000-0002-3189-1673
Kil, Hae Keum(길혜금)
Kim, Won Oak(김원옥)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/111805
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