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개흉술 후 통증관리를 위한 ropivacaine의 흉부 경막외 지속 주입시 sufentanil의 적정 병용 용량

Other Titles
 An Optimal Regimen of 0.2% Ropivacaine-Sufentanil as a Continuous Thoracic Epidural Infusion for Pain Control after Thoracotomy 
 김미경  ;  곽영란  ;  윤덕미  ;  최병인  ;  이종화 
 KOREAN JOURNAL OF ANESTHESIOLOGY, Vol.47(4) : 532-536, 2004 
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Issue Date
epidural analgesia ; sufentanil ; ropivacaine ; thoracotomy
BACKGROUND: Thoracotomy is considered one of the most painful surgical procedures. Thus optimal pain control is essential in the postoperative care of thoracotomy patients. In this randomized double-blinded study, we sought to determine an optimal dose-combination of sufentanil and ropivacaine 0.2% for postoperative epidural analgesia. METHODS: Forty-five of fifty-two patients that underwent thoracotomy were assigned to three groups to receive continuous high thoracic epidural analgesia with ropivacaine 0.2% + sufentanil 0.5µg/ml (group I), ropivacaine 0.2% + sufentanil 0.75µg/ml (group II), or ropivacaine 0.2% + sufentanil 1.0µg/ml (group III). Upon completion of surgery, a thoracic epidural catheter was inserted at the T1-3 level, and moved downward by 5-7 cm. Epidural continuous infusion was administered at 5 ml/hr. Resting VAS (visual analogue scale), dynamic VAS, forced vital capacity, and side effects were recorded at three times: immediate after extubation; 12 hours after arrival at the ICU; and 24 hours after arrival at the ICU. RESULTS: Resting VAS was significantly lower in group III immediately after extubation (P < 0.05) and dynamic VAS was significantly lower in group III immediately after extubation, and 12 hours after arriving at the ICU (P < 0.05) than in the other two groups. The differences in ketorolac dosing number, sedation scores, respiratory depression, pruritus, nausea/vomiting, and motor block were not significant between the three groups. CONCLUSIONS: We conclude that the combination of ropivacaine 0.2% and sufentanil 1.0µg/ml provides effective analgesia for post-thoracotomy pain with fewer side effects than the other two combinations tested.
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1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Kwak, Young Lan(곽영란) ORCID logo https://orcid.org/0000-0002-2984-9927
Kim, Mi Kyeong(김미경)
Yoon, Duck Mi(윤덕미)
Lee, Jong Wha(이종화)
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