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Triphasic mitral inflow velocity with middiastolic filling: clinical implications and associated echocardiographic findings

Authors
 Jong-Won Ha  ;  Jae K Oh  ;  A.Jamil Tajik  ;  James B Seward  ;  Keiji Ujino  ;  Margaret M Redfield 
Citation
 JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, Vol.17(5) : 428-431, 2004 
Journal Title
 JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY 
ISSN
 0894-7317 
Issue Date
2004
MeSH
Aged ; Aortic Valve Stenosis/physiopathology ; Blood Flow Velocity ; Cardiomyopathies/physiopathology ; Diastole ; Echocardiography, Doppler, Pulsed* ; Female ; Humans ; Hypertension/physiopathology ; Male ; Mitral Valve/physiopathology* ; Ventricular Function, Left*
Abstract
To explore underlying mechanisms and clinical implications of middiastolic filling, we measured early and late mitral inflow velocities, deceleration time of early mitral inflow velocity, and early diastolic mitral annular velocity (E′) recorded by pulsed wave Doppler echocardiography in 3 cardiac cycles of 35 patients with prominent mitral inflow (middiastolic flow velocity ≥ 0.2 m/s). E′ was measured at the septal corner of the mitral annulus by Doppler tissue echocardiography from the apical 4-chamber view and was found to be reduced (E′ < 0.1 m/s) in all patients; early mitral inflow velocity/E′ ratio was > 10 in all but 1 patient. Valsalva maneuver unmasked delayed relaxation in 15 (88%) of 17 patients and abolished middiastolic filling in 10 (59%). Triphasic mitral inflow with middiastolic flow is related to elevated filling pressure, delayed myocardial relaxation, and slow heart rate, indicating advanced diastolic dysfunction.
Full Text
http://www.sciencedirect.com/science/article/pii/S0894731704001531
DOI
10.1016/j.echo.2004.02.007
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Ha, Jong Won(하종원) ORCID logo https://orcid.org/0000-0002-8260-2958
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/111681
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