23 applicants were randomly divided into 3 groups(A, B, C) In group A, 25 unit of BTX -A was unilaterally Injected into masseter muscle(bilaterally 50 unit) and in group B, 35 unit was unilaterally injected(bilaterally 70 unit) In group C, controlled group, normal saline was injected.
In each of them, EMG was examined before Injection and 2weeks, 4weeks, 8weeks, 12weeks, 24 weeks after Injection.
The changes of EMG value was Insighted by elapsed time in each group, and at each time, the differences of th change of EMG value was also Investigated among the groups Then these results were analysed statistically.
The conclusions of this study were followings:
1. In two groups with BTX-A Injection, EMG activity of masseter muscles was reduced and It was suddenly reduced within 2weeks after injection.
2. From 8weeks after Injection, EMG activity of masseter muscles began to rebound, but at 24 weeks after injection, was still lower than that of pre-injection.
3. More reduction was not occurred In the group B than In the group A and therapeutic effect also was not maintained longer In the group B than In the group A In addition, rebound of EMG value was more In group 13 than 10 group A.
4. Even though EMG activity of masseter muscle was reduced, there was no change In the EMG activity of temporal muscle.