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혈당 조절 후 호전된 당뇨병성 당원축적증에 의한 간비대 1예

Other Titles
 A Case of Hepatomegaly due to Diabetic Glycogenosis Reversed by Glycemic Control 
 박진아  ;  송대훈  ;  이현철  ;  김경래  ;  임승길  ;  차봉수  ;  안철우  ;  김똘미  ;  김철식  ;  남주영  ;  박종숙 
 Journal of Korea Society of Endocrinology (대한내분비학회지), Vol.19(2) : 223-228, 2004 
Journal Title
 Journal of Korea Society of Endocrinology  (대한내분비학회지) 
Issue Date
Diabetes mellitus is well known to be associated with various structural and functional liver abnormalities. If diabetic patients are accompanied by hepatomegaly or abnormal findings from a liver function test, the most common pathological findings are steatosis and glycogenosis. The steatosis is characterized by deposition of macrovesicular fat droplets in the hepatocytes, which is common in obese, type 2 diabetes mellitus. If macrovesicular steatosis is combined with mixed inflammatory infiltrate, without evidence of alcoholic hepatitis, the case could be diagnosed as nonalcoholic steatohepatitis (NASH). NASH has the possibility of progressing to cirrhosis. Secondary glycogenosis is common in uncontrolled type 1 diabetes mellitus, and is completely reversible. A 22-year-old male, with uncontrolled type 1 diabetes mellitus, was admitted with anorexia, nausea and right upper quadrant pain. Hepatomegaly and elevated aminotransferases were noted. He was diagnosed as diabetic glycogenosis using computed tomogram and liver biopsy. The hepatomegaly and liver function test abnormalities were markedly improved with glycemic control
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1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
Yonsei Authors
김경래(Kim, Kyung Rae)
김똘미(Kim, Dol Mi)
김철식(Kim, Chul Sik)
김혜령(Kim, Hae Ryoung)
남주영(Nam, Ju Young)
박종숙(Park, Jong Suk) ORCID logo https://orcid.org/0000-0002-5385-1373
박찬일(Park, Chan Il)
안철우(Ahn, Chul Woo)
이현철(Lee, Hyun Chul)
임승길(Lim, Sung Kil)
차봉수(Cha, Bong Soo) ORCID logo https://orcid.org/0000-0003-0542-2854
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