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Prevalence of inducible clindamycin resistance in staphylococcal isolates at a Korean Tertiary Care Hospital

DC FieldValueLanguage
dc.contributor.author용동은-
dc.contributor.author이경원-
dc.contributor.author염종화-
dc.date.accessioned2015-06-10T13:02:51Z-
dc.date.available2015-06-10T13:02:51Z-
dc.date.issued2006-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/110910-
dc.description.abstractClindamycin resistance in Staphylococcus species can be either constitutive or inducible. Inducible resistance cannot be detected by the conventional antimicrobial susceptibility test. In this study, we determined the prevalence of inducible clindamycin resistance in staphylococcal isolates at a Korean tertiary care hospital. Between February and September 2004, 1,519 isolates of Staphylococcus aureus and 1,043 isolates of coagulase-negative staphylococci (CNS) were tested for inducible resistance by the D-zone test. Overall, 17% of MRSA, 84% of MSSA, 37% of MRCNS, and 70% of MSCNS were susceptible to clindamycin. Of the erythromycin non-susceptible, clindamycin-susceptible isolates, 32% of MRSA, 35% of MSSA, 90% of MRCNS, and 94% of MSCNS had inducible clindamycin resistance. Inducible clindamycin resistance in staphylococci was highly prevalent in Korea. This study indicates importance of the D-zone test in detecting inducible clindamycin resistance in staphylococci to aid in the optimal treatment of patients.-
dc.description.statementOfResponsibilityopen-
dc.format.extent480~484-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAnti-Bacterial Agents/pharmacology*-
dc.subject.MESHAnti-Infective Agents/pharmacology*-
dc.subject.MESHClindamycin/pharmacology*-
dc.subject.MESHDrug Resistance, Microbial*-
dc.subject.MESHDrug Resistance, Multiple, Bacterial-
dc.subject.MESHHumans-
dc.subject.MESHKorea-
dc.subject.MESHMicrobial Sensitivity Tests*-
dc.subject.MESHPrevalence-
dc.subject.MESHStaphylococcal Infections/metabolism*-
dc.subject.MESHStaphylococcus aureus/metabolism-
dc.titlePrevalence of inducible clindamycin resistance in staphylococcal isolates at a Korean Tertiary Care Hospital-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthorHwan Sub Lim-
dc.contributor.googleauthorHyukmin Lee-
dc.contributor.googleauthorKyoung Ho Roh-
dc.contributor.googleauthorJong Hwa Yum-
dc.contributor.googleauthorDongeun Yong-
dc.contributor.googleauthorKyungwon Lee-
dc.contributor.googleauthorYunsop Chong-
dc.identifier.doi10.3349/ymj.2006.47.4.480-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02423-
dc.contributor.localIdA02649-
dc.contributor.localIdA02352-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid16941736-
dc.subject.keywordStaphylococcus-
dc.subject.keywordclindamycin-
dc.subject.keywordantibiotic resistance-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.alternativeNameLee, Kyung Won-
dc.contributor.alternativeNameYum, Jong Hwa-
dc.contributor.affiliatedAuthorYong, Dong Eun-
dc.contributor.affiliatedAuthorLee, Kyung Won-
dc.contributor.affiliatedAuthorYum, Jong Hwa-
dc.rights.accessRightsfree-
dc.citation.volume47-
dc.citation.number4-
dc.citation.startPage480-
dc.citation.endPage484-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.47(4) : 480-484, 2006-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
5. Research Institutes (연구소) > Research Institute of Bacterial Resistance (세균내성연구소) > 1. Journal Papers

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