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조직 재생을 위한 Poly (D, L-lactide-co-glycolide) 표면에 (1→3)(1→6)-ßglucan 고정에 대한 세포 점착 및 성장 효과
DC Field | Value | Language |
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dc.contributor.author | 박종철 | - |
dc.date.accessioned | 2015-06-10T13:00:39Z | - |
dc.date.available | 2015-06-10T13:00:39Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 1229-0807 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/110845 | - |
dc.description.abstract | We examined the effects of -glucan-reinforced PLGA film and scaffold on HDFs (human dermal fibroblast) attachment and proliferation. The PLGA films were prepared by simple solvent-casting method. The prepared films were grafted with (1→3)(1→6)-ß-glucan in various ratios after plasma treatment on surface. The surface of the film was characterized by contact angle measure ment, scanning electron microscope (SEM), and Fourier-transform infrared spectrophotometer (FT-IR). The amount of (1→3)(1→6)-ß-glucan in the prepared film was indirectly determined by phenol-sulfuric acid method. The HDFs (Human dermal fibroblasts) were used to evaluate the cell attachment and proliferation on PLGA specimens before and after plasma/ß-glucan treatment. The result showed that the plasma treated groups exhibited more mont of ß-glucan might be grafted than the non plasma treated groups. Cell attachment was significantly enhanced in the plasma/ß-glucan grafted group after 4 hours incubation (p<0.05) due to the improved hydrophilicity and cytoactivity effect of the ß-glucan The cell proliferation of plasma/ß-glucan(2mg/ml) grafted group was the highest rate among the groups (p<0.05). | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 218~223 | - |
dc.relation.isPartOf | Journal of Biomedical Engineering Research (의공학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 조직 재생을 위한 Poly (D, L-lactide-co-glycolide) 표면에 (1→3)(1→6)-ßglucan 고정에 대한 세포 점착 및 성장 효과 | - |
dc.title.alternative | Surface Immobilization of ß-(1→3)(1→6)-glucan onto Biodegradable Polymer for Tissue Regeneration | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Medical Engineering (의학공학) | - |
dc.contributor.googleauthor | 이상길 | - |
dc.contributor.googleauthor | 이정복 | - |
dc.contributor.googleauthor | 유성미 | - |
dc.contributor.googleauthor | 박종철 | - |
dc.contributor.googleauthor | 최재봉 | - |
dc.contributor.googleauthor | 김정구 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01662 | - |
dc.relation.journalcode | J01263 | - |
dc.subject.keyword | tissue regeneration | - |
dc.subject.keyword | PLGA | - |
dc.subject.keyword | ß-glucan | - |
dc.subject.keyword | plasma treatment | - |
dc.subject.keyword | cell affinity | - |
dc.contributor.alternativeName | Park, Jong Chul | - |
dc.contributor.affiliatedAuthor | Park, Jong Chul | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 27 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 218 | - |
dc.citation.endPage | 223 | - |
dc.identifier.bibliographicCitation | Journal of Biomedical Engineering Research (의공학회지), Vol.27(5) : 218-223, 2006 | - |
dc.identifier.rimsid | 54480 | - |
dc.type.rims | ART | - |
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