십이지장 제 2부에서 점막 ‘백색 변조’의 의의 - 위 기능면에서 -

Abstract

Background/Aims: A mucosal `whitish discoloration` of the duodenal second portion may be discorvered during esophagogastroduodenoscopy (EGD). This study investigated the gastric functional implication and histological abnormalities of mucosal `whitish discoloration`. Methods: The upper gastrointestinal symptoms, gastric emptying time and histology findings were compared in patients with functional dyspepsia (FD) showing mucosal `whitish discoloration` of the duodenal second portion (group I), FD patients without `whitish discoloration` (group II), and normal controls who have neither symptoms nor `whitish discoloration` (normal controls). Results: There was a significant difference between group I (147.6 min) and group II (99.6 min) or normal controls (75.8 min). However there was no difference between group II and normal controls. There was no histological difference in the three groups. In particular, there was no mucosal infiltration of macrophage in second portion of duodenum. Conclusions: Mucosal `whitish discoloration` of the duodenal second portion, uncommon occurrence in EGD, can be correlated with a delayed gastric emptying time.