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악성 소화기 종양에서 F-18 FDG PET 또는 PET/CT 검사의 의의

Other Titles
 Roles of F-18 FDG PET or PET/CT for the Evaluation of Gastrointestinal Malignancies 
 윤미진  ;  김병일 
 Korean Journal of Gastroenterology, Vol.48(6) : 378-387, 2006 
Journal Title
 Korean Journal of Gastroenterology (대한소화기학회지) 
Issue Date
Gastric cancer ; Colon cancer ; F-18 FDG PET ; PET/CT
18F-FDG PET scan is an useful functional whole body imaging modality that images various types of malig­nancies with relative high sensitivity and specificity in a reasonably rapid time. It depicts a lesion based on abnormal glucose metabolism whereas CT detects malignant process mostly based on altered anatomy. In patients with gastric cancers, PET scan detects only less than 50% of early cancers and 62-98% of advanced cancers. For initial T staging, anatomical imaging with a high spatial resolution is essential. There are a few studies on the prognostic significance of FDG uptake with inconsistent results. In spite of low sensitivity for lymph node staging, the specificity of CT and PET scan are very high, and the specificity of PET scan tends to be higher than that of CT. Detection of distant metastases on PET scan is dependent on tumor histology, degree of FDG uptake in primary tumors, sites of distant metastases, etc. There are only a few data available for the evaluation of recurrence detection and treatment responses using FDG PET scan. FDG PET scan has been used in the preoperative staging of colorectal cancer with some promising results. It seems to be the most useful in restaging recurrent tumors and selecting those patients who would benefit from surgery. PET scan has a potential value in assessing treatment responses after various combination of treatments in patients with colorectal cancer.
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1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
Yonsei Authors
Yun, Mi Jin(윤미진) ORCID logo https://orcid.org/0000-0002-1712-163X
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