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Mitomycin C inhibits recurrent avellino dystrophy after phototherapeutic keratectomy

DC FieldValueLanguage
dc.contributor.author김응권-
dc.contributor.author김태임-
dc.date.accessioned2015-06-10T12:49:00Z-
dc.date.available2015-06-10T12:49:00Z-
dc.date.issued2006-
dc.identifier.issn0277-3740-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/110496-
dc.description.abstractPURPOSE: To report 4 patients with Avellino corneal dystrophy (ACD) who were treated with 0.02% mitomycin C (MMC) during phototherapeutic keratectomy (PTK). METHODS: ACD was confirmed by polymorphism of the exon region in the BIGH3 gene using polymerase chain reaction followed by DNA sequencing analysis. Three patients with recurrent ACD and 1 patient with primary ACD underwent PTK. Intraoperative 0.02% MMC was applied topically with a soaked microsponge. RESULTS: There was no recurrence of ACD in the heterozygotes, but there were recurrences with best-corrected visual acuity of 20/30 in the 2 homozygotes. CONCLUSION: Intraoperative use of topical 0.02% MMC in conjunction with PTK may prevent or delay the recurrence of ACD for at least for 1 year.-
dc.description.statementOfResponsibilityopen-
dc.format.extent220~223-
dc.relation.isPartOfCornea-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHCorneal Dystrophies, Hereditary/drug therapy-
dc.subject.MESHCorneal Dystrophies, Hereditary/pathology-
dc.subject.MESHCorneal Dystrophies, Hereditary/surgery*-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHIntraoperative Period-
dc.subject.MESHLasers, Excimer-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMitomycin/administration & dosage*-
dc.subject.MESHMitomycin/therapeutic use-
dc.subject.MESHNucleic Acid Synthesis Inhibitors/administration & dosage*-
dc.subject.MESHNucleic Acid Synthesis Inhibitors/therapeutic use-
dc.subject.MESHOphthalmic Solutions-
dc.subject.MESHPhotorefractive Keratectomy*-
dc.subject.MESHSecondary Prevention-
dc.subject.MESHVisual Acuity-
dc.titleMitomycin C inhibits recurrent avellino dystrophy after phototherapeutic keratectomy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학)-
dc.contributor.googleauthorTae-im Kim-
dc.contributor.googleauthorJhang Ho Pak-
dc.contributor.googleauthorJu-byung Chae-
dc.contributor.googleauthorEung Kweon Kim-
dc.contributor.googleauthorHungwon Tchah-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00831-
dc.contributor.localIdA01080-
dc.relation.journalcodeJ00648-
dc.identifier.pmid16371787-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00003226-200602000-00020&LSLINK=80&D=ovft-
dc.subject.keywordAvellino corneal dystrophy-
dc.subject.keywordmitomycin C-
dc.subject.keywordphoto-therapeutic keratectomy-
dc.contributor.alternativeNameKim, Eung Kweon-
dc.contributor.alternativeNameKim, Tae Im-
dc.contributor.affiliatedAuthorKim, Eung Kweon-
dc.contributor.affiliatedAuthorKim, Tae Im-
dc.rights.accessRightsnot free-
dc.citation.volume25-
dc.citation.number2-
dc.citation.startPage220-
dc.citation.endPage223-
dc.identifier.bibliographicCitationCornea, Vol.25(2) : 220-223, 2006-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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