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Mitomycin C inhibits recurrent avellino dystrophy after phototherapeutic keratectomy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김응권 | - |
dc.contributor.author | 김태임 | - |
dc.date.accessioned | 2015-06-10T12:49:00Z | - |
dc.date.available | 2015-06-10T12:49:00Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0277-3740 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/110496 | - |
dc.description.abstract | PURPOSE: To report 4 patients with Avellino corneal dystrophy (ACD) who were treated with 0.02% mitomycin C (MMC) during phototherapeutic keratectomy (PTK). METHODS: ACD was confirmed by polymorphism of the exon region in the BIGH3 gene using polymerase chain reaction followed by DNA sequencing analysis. Three patients with recurrent ACD and 1 patient with primary ACD underwent PTK. Intraoperative 0.02% MMC was applied topically with a soaked microsponge. RESULTS: There was no recurrence of ACD in the heterozygotes, but there were recurrences with best-corrected visual acuity of 20/30 in the 2 homozygotes. CONCLUSION: Intraoperative use of topical 0.02% MMC in conjunction with PTK may prevent or delay the recurrence of ACD for at least for 1 year. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 220~223 | - |
dc.relation.isPartOf | CORNEA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Corneal Dystrophies, Hereditary/drug therapy | - |
dc.subject.MESH | Corneal Dystrophies, Hereditary/pathology | - |
dc.subject.MESH | Corneal Dystrophies, Hereditary/surgery* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intraoperative Period | - |
dc.subject.MESH | Lasers, Excimer | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Mitomycin/administration & dosage* | - |
dc.subject.MESH | Mitomycin/therapeutic use | - |
dc.subject.MESH | Nucleic Acid Synthesis Inhibitors/administration & dosage* | - |
dc.subject.MESH | Nucleic Acid Synthesis Inhibitors/therapeutic use | - |
dc.subject.MESH | Ophthalmic Solutions | - |
dc.subject.MESH | Photorefractive Keratectomy* | - |
dc.subject.MESH | Secondary Prevention | - |
dc.subject.MESH | Visual Acuity | - |
dc.title | Mitomycin C inhibits recurrent avellino dystrophy after phototherapeutic keratectomy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | Tae-im Kim | - |
dc.contributor.googleauthor | Jhang Ho Pak | - |
dc.contributor.googleauthor | Ju-byung Chae | - |
dc.contributor.googleauthor | Eung Kweon Kim | - |
dc.contributor.googleauthor | Hungwon Tchah | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00831 | - |
dc.contributor.localId | A01080 | - |
dc.relation.journalcode | J00648 | - |
dc.identifier.eissn | 1536-4798 | - |
dc.identifier.pmid | 16371787 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00003226-200602000-00020&LSLINK=80&D=ovft | - |
dc.subject.keyword | Avellino corneal dystrophy | - |
dc.subject.keyword | mitomycin C | - |
dc.subject.keyword | photo-therapeutic keratectomy | - |
dc.contributor.alternativeName | Kim, Eung Kweon | - |
dc.contributor.alternativeName | Kim, Tae Im | - |
dc.contributor.affiliatedAuthor | Kim, Eung Kweon | - |
dc.contributor.affiliatedAuthor | Kim, Tae Im | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 25 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 220 | - |
dc.citation.endPage | 223 | - |
dc.identifier.bibliographicCitation | CORNEA, Vol.25(2) : 220-223, 2006 | - |
dc.identifier.rimsid | 39210 | - |
dc.type.rims | ART | - |
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