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신생혈관녹내장 환자의 방수내 변형성장인자-β와 혈관내피성장인자 농도와 아메드밸브 수술 결과
DC Field | Value | Language |
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dc.contributor.author | 김찬윤 | - |
dc.contributor.author | 이준행 | - |
dc.date.accessioned | 2015-06-10T12:48:50Z | - |
dc.date.available | 2015-06-10T12:48:50Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0378-6471 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/110491 | - |
dc.description.abstract | Purpose: To assess the relationship of transforming growth factor- ( β β TGF- ) and vascular endothelial growth factor (VEGF) levels in the aqueous humor of neovascular glaucoma (NVG) patients and the results of Ahmed valve implantation surgery. Methods: We compared surgical outcomes of NVG patients who underwent Ahmed valve implant surgery from January 2002 through October 2002 at severance hospital with levels of TGF- 1, TGF- 2 and VEGF β β in the aqueous humors of these patients. Results: Nineteen eyes (19 patients) were analyzed in the study. The success of surgery was defined as intraocular pressure maintained as 6-20 mm Hg regardless of additional glaucoma medications taken. Twelve eyes (63%) satisfied successful surgery. TGF- 1 concentrat β ion was 1.51 ng/ml in the success group and 2.31 ng/ml in the failed group (p=0.295). TGF- 2 concentration wa β s 5.19 ng/ml in the success group and 5.73ng/ml in the failed group (p=0.367). VEGF concentration was 10.21 ng/ml in the success group and 9.87ng/ml in the failed group (p=0.516). All showed no statistical difference between the groups. Conclusions: In our study, no significant relationship between levels of TGF- 1, TGF- 2, or VEGF in the β β aqueous humor and the surgical outcomes of Ahmed valve implantation were found in patients with NVG. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 571~576 | - |
dc.relation.isPartOf | JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 신생혈관녹내장 환자의 방수내 변형성장인자-β와 혈관내피성장인자 농도와 아메드밸브 수술 결과 | - |
dc.title.alternative | Ahmed Valve Implantation Result and TGF-?and VEGF in the Aqueous Humor of Neovascular Glaucoma Patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | 송원경 | - |
dc.contributor.googleauthor | 이준행 | - |
dc.contributor.googleauthor | 홍영재 | - |
dc.contributor.googleauthor | 김찬윤 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01035 | - |
dc.contributor.localId | A03180 | - |
dc.relation.journalcode | J01838 | - |
dc.identifier.eissn | 2092-9374 | - |
dc.subject.keyword | Ahmed valve | - |
dc.subject.keyword | Neovascular glaucoma | - |
dc.subject.keyword | Transforming growth factor- | - |
dc.subject.keyword | Vascular endothelial growth factor | - |
dc.contributor.alternativeName | Kim, Chan Yun | - |
dc.contributor.alternativeName | Lee, Joon Haeng | - |
dc.contributor.affiliatedAuthor | Kim, Chan Yun | - |
dc.contributor.affiliatedAuthor | Lee, Joon Haeng | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 47 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 571 | - |
dc.citation.endPage | 576 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY, Vol.47(4) : 571-576, 2006 | - |
dc.identifier.rimsid | 39205 | - |
dc.type.rims | ART | - |
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