Cited 54 times in
Effects of Topical Antiglaucoma Application on Conjunctival Impression Cytology Specimens
DC Field | Value | Language |
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dc.contributor.author | 서경률 | - |
dc.contributor.author | 성공제 | - |
dc.contributor.author | 이승규 | - |
dc.contributor.author | 홍사민 | - |
dc.contributor.author | 홍영재 | - |
dc.date.accessioned | 2015-06-10T12:38:20Z | - |
dc.date.available | 2015-06-10T12:38:20Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0002-9394 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/110175 | - |
dc.description.abstract | PURPOSE: To evaluate the changes in conjunctival impression cytology specimens from patients receiving various topical antiglaucoma medications. DESIGN: Cross-sectional comparative study. METHODS: Impression cytology specimens were obtained from the eyes taking no topical medication (n = 20) and from the eyes taking various antiglaucoma medications (timolol n = 34; latanoprost n = 40; dorzolamide n = 32; timolol + latanoprost n = 30; timolol + dorzolamide n = 34). Specimens were graded on a scale of zero to three according to Nelson's method. RESULTS: Cytology scores were significantly higher in the medication group than the control group. Mean cytology scores of the control, timolol, latanoprost, dorzolamide, timolol + latanoprost, and timolol + dorzolamide group were 0.20, 1.62, 2.00, 1.75, 2.13, and 2.44, respectively. Among the medication groups, cytology scores were significantly lower in the monotherapy group than the fixed-combination therapy group. CONCLUSIONS: Various topical antiglaucoma medications induce a significant degree of squamous metaplasia. Conjunctival surface could be altered after the long-term use of antiglaucoma medication. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 185~186 | - |
dc.relation.isPartOf | AMERICAN JOURNAL OF OPHTHALMOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Administration, Topical | - |
dc.subject.MESH | Antihypertensive Agents/administration & dosage* | - |
dc.subject.MESH | Conjunctiva/drug effects* | - |
dc.subject.MESH | Conjunctiva/pathology* | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Drug Therapy, Combination | - |
dc.subject.MESH | Epithelium/drug effects | - |
dc.subject.MESH | Epithelium/parasitology | - |
dc.subject.MESH | Glaucoma, Open-Angle/drug therapy* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Latanoprost | - |
dc.subject.MESH | Metaplasia | - |
dc.subject.MESH | Prostaglandins F, Synthetic/administration & dosage | - |
dc.subject.MESH | Sulfonamides/administration & dosage | - |
dc.subject.MESH | Thiophenes/administration & dosage | - |
dc.subject.MESH | Timolol/administration & dosage | - |
dc.title | Effects of Topical Antiglaucoma Application on Conjunctival Impression Cytology Specimens | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | Samin Hong | - |
dc.contributor.googleauthor | Christopher Seungkyu Lee | - |
dc.contributor.googleauthor | Kyoung Yul Seo | - |
dc.contributor.googleauthor | Gong Je Seong | - |
dc.contributor.googleauthor | Young Jae Hong | - |
dc.identifier.doi | 10.1016/j.ajo.2006.02.056 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01870 | - |
dc.contributor.localId | A01946 | - |
dc.contributor.localId | A02913 | - |
dc.contributor.localId | A04395 | - |
dc.contributor.localId | A04416 | - |
dc.relation.journalcode | J00097 | - |
dc.identifier.eissn | 1879-1891 | - |
dc.identifier.pmid | 16815281 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0002939406003515 | - |
dc.contributor.alternativeName | Seo, Kyuong Yul | - |
dc.contributor.alternativeName | Seong, Gong Je | - |
dc.contributor.alternativeName | Lee, Seung Kyu | - |
dc.contributor.alternativeName | Hong, Sa Min | - |
dc.contributor.alternativeName | Hong, Young Jae | - |
dc.contributor.affiliatedAuthor | Seo, Kyuong Yul | - |
dc.contributor.affiliatedAuthor | Seong, Gong Je | - |
dc.contributor.affiliatedAuthor | Lee, Seung Kyu | - |
dc.contributor.affiliatedAuthor | Hong, Sa Min | - |
dc.contributor.affiliatedAuthor | Hong, Young Jae | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 142 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 185 | - |
dc.citation.endPage | 186 | - |
dc.identifier.bibliographicCitation | AMERICAN JOURNAL OF OPHTHALMOLOGY, Vol.142(1) : 185-186, 2006 | - |
dc.identifier.rimsid | 52544 | - |
dc.type.rims | ART | - |
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