Hypopigmented mycosis fungoides has been infrequently described as a variant of mycosis fungoides. It mostly occurs in dark-skinned or Asian patients, particularly children, and is often misdiagnosed as a different condition, such as vitiligo, chronic lichenoid pityriasis or postinflammatory hypopigmentation because of its non-specific manifestations. We herein describe a Korean case of hypopigmented mycosis fungoides which was misdiagnosed as a vitiligo. We also emphasize the importance of a biopsy on any persistent or unusual hypopigmented lesion to avoid delay in the diagnosis of mycosis fungoides.