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병리학적 병기 T3 방광이행세포암에서 신보조적 체외 방사선치료의 효과

Other Titles
 The Effects of Neoadjuvant External Beam Radiotherapy on Pathologic Stage T3 Bladder Transitional Cell Carcinoma 
Authors
 김성수  ;  양원재  ;  조재호  ;  홍성준 
Citation
 KOREAN JOURNAL OF UROLOGY, Vol.47(3) : 232-236, 2006 
Journal Title
KOREAN JOURNAL OF UROLOGY(대한비뇨기과학회지)
ISSN
 0494-4747 
Issue Date
2006
Keywords
Bladder neoplasms ; Radiotherapy ; Cystectomy
Abstract
Purpose: Our study was conducted to compare the effects of neoadjuvant external beam radiotherapy and radical cystectomy to surgery alone for the patients suffering with pathologic stage T3 (pT3) bladder transitional cell carcinoma (TCCa). Materials and Methods: We retrospectively analyzed 45 patients who were diagnosed between 1990 and 1998 as having pT3 bladder TCCa in their final cystectomy specimens. Among them, 22 patients underwent preoperative external beam radiotherapy, and the other 23 patients underwent radical cystectomy alone. The radiation consisted of a total dose of 2,000 cGy delivered to the pelvis in 5 equal fractions that consisted of 400cGy daily. Systemic chemotherapy was not used in either group unless there was evidence of recurrent disease. Results: There were no preoperative demographic differences between the two groups. The local recurrence rate was significantly lower in the preoperative radiotherapy group (p=0.0397), but the overall survival rate was not significantly different (p=0.2695). The distant metastasis free survival rate was not significantly different between the two groups (p=0.4682). Conclusions: We have shown that preoperative radiotherapy is an effective way to achieve local control of locoregionally advanced (pT3) bladder TCCa. However, our study did not have sufficient statistical power to identify a survival difference between the two groups.
Files in This Item:
T200600965.pdf Download
DOI
10.4111/kju.2006.47.3.232
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Hong, Sung Joon(홍성준) ORCID logo https://orcid.org/0000-0001-9869-065X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/109921
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