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중등도의 허혈성 승모판막 폐쇄부전 환자의 관상동맥 우회로 조성술 시 승모판막 수술의 유무에 따른 임상 결과

Other Titles
 Clinical Results of Mitral Valvular Surgery in Patients with Moderate Ischemic Mitral Regurgitation Undergoing Coronary Artery Bypass Grafting 
Authors
 유송현  ;  홍유선  ;  장병철  ;  유경종  ;  강면식 
Citation
 Korean Journal of Thoracic and Cardiovascular Surgery (대한흉부외과학회지), Vol.39(8) : 611-618, 2006 
Journal Title
 Korean Journal of Thoracic and Cardiovascular Surgery (대한흉부외과학회지) 
ISSN
 2233-601X 
Issue Date
2006
Keywords
Ischemic mitral regurgitaion ; Coronary artery bypass grafting
Abstract
Background: There have been controversies whether mitral valvular surgery is necessary in the patients with moderate ischemic mitral regurgitation undergoing coronary artery bypass grafting. The purpose of this study is to evaluate the long term clinical results of patients with moderate ischemic mitral regurgitation. Material and Method: Between January 1992 and February 2005, 44 patients with moderate ischemic mitral regurgitation underwent coronary artery bypass grafting. Concomitant mitral valvular procedure was performed in 20 patients (group 1) and isolated coronary artery bypass grafting was performed in 24 patients (group 2). There were no significant difference between groups except cardiopulmonary bypass time (p<0.01). Postoperative follow up duration was 30.1±29.6 months and last follow up echocardiographic examination was performed at 21.2±28.0 months. Result: There was no difference in operative mortality between groups (group 1 vs group 2, 15.0% vs 8.3%, p=0.493). Grade of mitral regurgitation (0.81±0.91 vs 1.50±0.05, p=0.046) and reduction in regurgitation grade (1.75±0.93 vs 0.70±1.26, p=0.009) were different between two groups. But there were no significant differences in left ventricular ejection fraction (34.1±11.4% vs 41.6±12.9%), left ventricular end systolic volume (118.2±63.9 mL vs 85.6±28.1 mL), New York Heart Association functional class (2.1±0.2 vs 2.4±1.2) and 5 year survival rate (85±8% vs 82±8%). There was no risk factor for operative mortality and the only risk factor for late death was preoperative atrial fibrillation (p=0.042). There was no significant correlation between mitral valvular surgery and late death. Conclusion: Concomitant mitral valvular procedure in patients with moderate ischemic mitral regurgitation undergoing coronary artery bypass grafting had no significant positive effect on survival and ventricular function compared with isolated coronary artery bypass grafting. Prospective randomized study may be needed to evaluate the necessity of concomitant mitral procedure and to find more effective method for the improvement of ventricular function.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Meyun Shick(강면식)
Yoo, Kyung Jong(유경종) ORCID logo https://orcid.org/0000-0002-9858-140X
Yu, Song Hyeon(유송현)
Chang, Byung Chul(장병철)
Hong, You Sun(홍유선)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/109915
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