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Enhanced Immunogenicity and Protective Efficacy with the Use of Interleukin-12-Encapsulated Microspheres plus AS01B in Tuberculosis Subunit Vaccination

DC Field Value Language
dc.contributor.author조상래-
dc.date.accessioned2015-06-10T12:28:20Z-
dc.date.available2015-06-10T12:28:20Z-
dc.date.issued2006-
dc.identifier.issn0019-9567-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/109863-
dc.description.abstractTuberculosis subunit vaccines codelivered with interleukin-12 (IL-12)-encapsulated microspheres (IL-12EM) are designed for a sustained release of IL-12 and could induce strong Th1 immune responses specific to Ag85A and ESAT-6. The adjuvant combination of IL-12EM plus AS01B was a more efficient way to induce a sustained Th1 immunity and protection against Mycobacterium tuberculosis.-
dc.description.statementOfResponsibilityopen-
dc.format.extent4954~4959-
dc.relation.isPartOfINFECTION AND IMMUNITY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAcyltransferases/immunology-
dc.subject.MESHAdjuvants, Immunologic*-
dc.subject.MESHAnimals-
dc.subject.MESHAntibodies, Bacterial/blood*-
dc.subject.MESHAntibodies, Bacterial/immunology-
dc.subject.MESHAntigens, Bacterial/immunology-
dc.subject.MESHBacterial Proteins-
dc.subject.MESHCapsules-
dc.subject.MESHDelayed-Action Preparations-
dc.subject.MESHInterleukin-12/immunology*-
dc.subject.MESHMice-
dc.subject.MESHMice, Inbred C57BL-
dc.subject.MESHMicrospheres*-
dc.subject.MESHMycobacterium tuberculosis/immunology-
dc.subject.MESHMycobacterium tuberculosis/pathogenicity-
dc.subject.MESHTh1 Cells/immunology-
dc.subject.MESHTuberculosis/immunology-
dc.subject.MESHTuberculosis/prevention & control*-
dc.subject.MESHTuberculosis Vaccines/administration & dosage-
dc.subject.MESHTuberculosis Vaccines/immunology*-
dc.subject.MESHVaccination-
dc.titleEnhanced Immunogenicity and Protective Efficacy with the Use of Interleukin-12-Encapsulated Microspheres plus AS01B in Tuberculosis Subunit Vaccination-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Microbiology (미생물학)-
dc.contributor.googleauthorSang-Jun Ha-
dc.contributor.googleauthorSu-Hyung Park-
dc.contributor.googleauthorHye-Ju Kim-
dc.contributor.googleauthorSeung-Chul Kim-
dc.contributor.googleauthorHyang-Ju Kang-
dc.contributor.googleauthorEun-Gae Lee-
dc.contributor.googleauthorSoon-Geon Kwon-
dc.contributor.googleauthorByong-Moon Kim-
dc.contributor.googleauthorSung-Hee Lee-
dc.contributor.googleauthorWon-Bae Kim-
dc.contributor.googleauthorYoung-Chul Sung-
dc.contributor.googleauthorSang-Nae Cho-
dc.identifier.doi10.1128/IAI.01781-05-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03824-
dc.relation.journalcodeJ01055-
dc.identifier.eissn1098-5522-
dc.identifier.pmid16861689-
dc.contributor.alternativeNameCho, Sang Nae-
dc.contributor.affiliatedAuthorCho, Sang Nae-
dc.rights.accessRightsfree-
dc.citation.volume74-
dc.citation.number8-
dc.citation.startPage4954-
dc.citation.endPage4959-
dc.identifier.bibliographicCitationINFECTION AND IMMUNITY, Vol.74(8) : 4954-4959, 2006-
dc.identifier.rimsid50646-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Microbiology (미생물학교실) > 1. Journal Papers

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