Cited 34 times in
Enhanced Immunogenicity and Protective Efficacy with the Use of Interleukin-12-Encapsulated Microspheres plus AS01B in Tuberculosis Subunit Vaccination
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 조상래 | - |
dc.date.accessioned | 2015-06-10T12:28:20Z | - |
dc.date.available | 2015-06-10T12:28:20Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0019-9567 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/109863 | - |
dc.description.abstract | Tuberculosis subunit vaccines codelivered with interleukin-12 (IL-12)-encapsulated microspheres (IL-12EM) are designed for a sustained release of IL-12 and could induce strong Th1 immune responses specific to Ag85A and ESAT-6. The adjuvant combination of IL-12EM plus AS01B was a more efficient way to induce a sustained Th1 immunity and protection against Mycobacterium tuberculosis. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 4954~4959 | - |
dc.relation.isPartOf | INFECTION AND IMMUNITY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Acyltransferases/immunology | - |
dc.subject.MESH | Adjuvants, Immunologic* | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Antibodies, Bacterial/blood* | - |
dc.subject.MESH | Antibodies, Bacterial/immunology | - |
dc.subject.MESH | Antigens, Bacterial/immunology | - |
dc.subject.MESH | Bacterial Proteins | - |
dc.subject.MESH | Capsules | - |
dc.subject.MESH | Delayed-Action Preparations | - |
dc.subject.MESH | Interleukin-12/immunology* | - |
dc.subject.MESH | Mice | - |
dc.subject.MESH | Mice, Inbred C57BL | - |
dc.subject.MESH | Microspheres* | - |
dc.subject.MESH | Mycobacterium tuberculosis/immunology | - |
dc.subject.MESH | Mycobacterium tuberculosis/pathogenicity | - |
dc.subject.MESH | Th1 Cells/immunology | - |
dc.subject.MESH | Tuberculosis/immunology | - |
dc.subject.MESH | Tuberculosis/prevention & control* | - |
dc.subject.MESH | Tuberculosis Vaccines/administration & dosage | - |
dc.subject.MESH | Tuberculosis Vaccines/immunology* | - |
dc.subject.MESH | Vaccination | - |
dc.title | Enhanced Immunogenicity and Protective Efficacy with the Use of Interleukin-12-Encapsulated Microspheres plus AS01B in Tuberculosis Subunit Vaccination | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Microbiology (미생물학) | - |
dc.contributor.googleauthor | Sang-Jun Ha | - |
dc.contributor.googleauthor | Su-Hyung Park | - |
dc.contributor.googleauthor | Hye-Ju Kim | - |
dc.contributor.googleauthor | Seung-Chul Kim | - |
dc.contributor.googleauthor | Hyang-Ju Kang | - |
dc.contributor.googleauthor | Eun-Gae Lee | - |
dc.contributor.googleauthor | Soon-Geon Kwon | - |
dc.contributor.googleauthor | Byong-Moon Kim | - |
dc.contributor.googleauthor | Sung-Hee Lee | - |
dc.contributor.googleauthor | Won-Bae Kim | - |
dc.contributor.googleauthor | Young-Chul Sung | - |
dc.contributor.googleauthor | Sang-Nae Cho | - |
dc.identifier.doi | 10.1128/IAI.01781-05 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03824 | - |
dc.relation.journalcode | J01055 | - |
dc.identifier.eissn | 1098-5522 | - |
dc.identifier.pmid | 16861689 | - |
dc.contributor.alternativeName | Cho, Sang Nae | - |
dc.contributor.affiliatedAuthor | Cho, Sang Nae | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 74 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 4954 | - |
dc.citation.endPage | 4959 | - |
dc.identifier.bibliographicCitation | INFECTION AND IMMUNITY, Vol.74(8) : 4954-4959, 2006 | - |
dc.identifier.rimsid | 50646 | - |
dc.type.rims | ART | - |
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