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담낭암의 근치 절제술 후 예후에 영향을 주는 인자에 대한 분석

Other Titles
 Analysis of Prognostic Factors after Curative Resection for Gallbladder Carcinoma 
Authors
 박준성  ;  윤동섭  ;  김경식  ;  최진섭  ;  이우정  ;  지훈상  ;  김병로 
Citation
 Korean Journal of Gastroenterology, Vol.48(1) : 32-36, 2006 
Journal Title
 Korean Journal of Gastroenterology (대한소화기학회지) 
ISSN
 1598-9992 
Issue Date
2006
MeSH
Aged ; Carcinoma/mortality ; Carcinoma/secondary ; Carcinoma/surgery* ; Female ; Gallbladder Neoplasms/mortality ; Gallbladder Neoplasms/pathology ; Gallbladder Neoplasms/surgery* ; Humans ; Lymphatic Metastasis ; Male ; Middle Aged ; Prognosis ; Survival Rate
Keywords
Gallbladder carcinoma ; Survival ; Prognostic factors ; Curative surgery
Abstract
Background/Aims: Despite the development in diagnostic tools, gallbladder carcinoma is often diagnosed at an advanced stage. Therefore, early diagnosis and radical resection are most important factors for the prognosis of gallbladder carcinoma. However, prognostic factors after radical resection of gallbladder carcinoma have not been well identified. The aim of this study was to evaluate the prognostic factors of gallbladder carcinoma after curative resection. Methods: We reviewed the records of the 115 patients with gallbladder carcinoma who underwent curative surgery between 1989 and 2004 at Yonsei University Medical Center (YUMC). The relationship between survival and clinicopathological variables was assessed. Results: In 311 patients presenting with gallbladder carcinoma, 195 patients (62.5%) were radically resected. Among 195 patients, 80 patients were excluded because of incomplete clinicopathologic data and unsatisfactory follow-up. The 5 year overall survival rate was 36.0%, and disease free 5 year survival rate was 3.9%. Univariate analysis showed that survival was closely related to gross morphology, depth of tumor invasion, lymph node metastasis and preoperative serum CA19-9 level. Three significant factors identified by multivariate analysis were depth of tumor invasion, gross morphology, and preoperative serum CA19-9 level. Conclusions: Depth of tumor invasion, gross morphology, and preoperative serum CA19-9 level are independent significant prognostic factors of resectable gallbladder carcinoma.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Sik(김경식) ORCID logo https://orcid.org/0000-0001-9498-284X
Kim, Byong Ro(김병로)
Yoon, Dong Sup(윤동섭) ORCID logo https://orcid.org/0000-0001-6444-9606
Lee, Woo Jung(이우정) ORCID logo https://orcid.org/0000-0001-9273-261X
Chi, Hoon Sang(지훈상)
Choi, Jin Sub(최진섭)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/109656
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