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방사능(99mTc-MIBI) 유도 최소 침습 부갑상선 절제술 시 위양성 병변

Other Titles
 False-Positive Parathyroid Sestamibi in Minimally Invasive Radioguided Parathyroidectomy 
Authors
 이잔디  ;  김승현  ;  장항석  ;  정웅윤  ;  박정수 
Citation
 JOURNAL OF THE KOREAN SURGICAL SOCIETY , Vol.70(2) : 144-147, 2006 
Journal Title
JOURNAL OF THE KOREAN SURGICAL SOCIETY (대한외과학회지)
ISSN
 1226-0053 
Issue Date
2006
Keywords
False-positive 99mTc-sestamibi scan ; Minimally invasive radio-guided parathyroidectomy (MIRGP) ; Parathyroid adenoma ; Parathyroid hyperplasia ; 위양성 99mTc-sestamibi scan ; 최소 절개 방사능 유도 부갑상선 절제술 ; 부갑상선 선종 ; 부갑상선 증식증
Abstract
A 99mTc-sestamibi scan has become the most widely used localizing test for identifying a parathyroid adenoma. Despite its popularity, the effectiveness of 99mTc-sestamibi scan for parathyroid localization is still controversial due to the large number of false-positive results. The false positive 99mTc- sestamibi scan can be attributed to a thyroid adenoma, nodular hyperplasia, metastatic thyroid cancer and other proliferating thyroid diseases because 99mTc-sestamibi is specific to the mitochondrial membrane of cells with high-level metabolic status, and not specific to the parathyroid itself. Minimally invasive radio-guided parathyroidectomy (MIRGP) was performed on a 61 year-old woman. The 99mTc-sestamibi focus was completely excised with γ-probe guidance. However, the frozen pathology showed the excised tissue to be a thyroid papillary carcinoma. We present the unexpected false-positive 99mTc-sestamibi in MIRGP, and discuss the considerations in order to reduce the number of false- positive parathyroid 99mTc-sestamibi scans.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Park, Cheong Soo(박정수)
Chang, Hang Seok(장항석) ORCID logo https://orcid.org/0000-0002-5162-103X
Chung, Woong Youn(정웅윤)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/109563
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