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다낭성난소증후군과 인슐린 저항성

Other Titles
 Polycystic Ovary Syndrome and Insulin Resistance 
Authors
 황주연  ;  이병석 
Citation
 Korean Journal of Obstetrics and Gynecology (대한산부인과학회지), Vol.49(6) : 1179-1187, 2006 
Journal Title
 Korean Journal of Obstetrics and Gynecology (대한산부인과학회지) 
ISSN
 2287-8572 
Issue Date
2006
Keywords
Polycystic ovary syndrome ; Hyperandrogenism ; Insulin resistance ; Insulin sensitizer
Abstract
Polycysytic Ovary Syndrome (PCOS) is a common endocrine disorder characterized by chronic anovulation and hyperandrogenism. The etiology of PCOS is complex and incompletely understood. Accumulating data conclude that hyperinsulinemia and hyperandrogenemia may cause hormonal abnormalities that lead to disturbance of ovarian function. Although insulin resistance is not a part of the diagnostic criteria for PCOS, its importance in its pathogenesis can not be ignored. Excess insulin is capable of stimulating steroidogenesis and therefore excessive androgen production occurs from the theca cell system. Recently, the effects of insulin sensitizer in PCOS patients are being reported and they include the improvement of menstrual pattern, improvement in hyperandrogenism, increased response in ovulation induction and prevention of cardiovascular diseases. Understanding the relation of PCOS and insulin resistance will offer an improvement in treatment of PCOS in the future.
Files in This Item:
T200600513.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Byung Seok(이병석) ORCID logo https://orcid.org/0000-0001-6001-2079
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/109372
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