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Analysis of renal biopsies performed in children with abnormal findings in urinary mass screening

 Young-Mock Lee  ;  Seoung-Yon Baek  ;  Ji Hong Kim  ;  Dong Soo Kim  ;  Jae Seung Lee  ;  Pyung-Kil Kim 
 ACTA PAEDIATRICA, Vol.95(7) : 849-853, 2006 
Journal Title
Issue Date
Child ; Female ; Hematuria/pathology ; Humans ; Kidney/pathology* ; Kidney Diseases/classification ; Kidney Diseases/pathology* ; Male ; Reference Values ; Urinalysis
BACKGROUND: School urinary mass screening tests are performed to make early diagnosis and provide proper treatment for chronic renal diseases. However, very few systemic analyses or studies have been reported regarding final diagnosis made on children with abnormal urinary screening results. AIM: To study the cases of renal biopsy in children detected in urinary screening. METHODS: We retrospectively analysed 461 cases of renal biopsy performed on children referred to us with abnormal school urinary mass screening results who satisfied indications for renal biopsy. RESULTS: Pathologically abnormal findings were observed in 285 (61.8%) patients. Thin glomerular basement membrane disease was detected in 127 (27.5%) cases and IgA nephropathy in 121 (26.2%) cases. Among those 461 children, microscopic haematuria was observed in 289 (62.7%) patients, proteinuria in nine (2.0%), and both in 163 (35.4%). In addition, a statistically higher rate of pathological abnormalities on renal biopsy was noted in the group with microscopic haematuria combined with proteinuria and also in cases with more severe haematuria. CONCLUSION: School urinary mass screening has greatly contributed to diagnosing chronic renal diseases. Continuous medical observation is required when abnormal urinalysis is observed, and a more aggressive medical approach such as renal biopsy should also be performed if necessary.
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1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Soo(김동수)
Kim, Ji Hong(김지홍) ORCID logo https://orcid.org/0000-0001-5352-5423
Lee, Young Mock(이영목) ORCID logo https://orcid.org/0000-0002-5838-249X
Lee, Jae Seung(이재승)
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