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양측성 뇌하수체 종양으로 인한 말단비대증 1예

Other Titles
 A Case of Acromegaly Caused by Double Pituitary Adenomas 
Authors
 김혜진  ;  김철식  ;  박종숙  ;  박진아  ;  공지현  ;  남지선  ;  안철우  ;  차봉수  ;  임승길  ;  김경래  ;  이현철  ;  홍순원 
Citation
 Journal of Korea Society of Endocrinology (대한내분비학회지), Vol.21(1) : 53-57, 2006 
Journal Title
 Journal of Korea Society of Endocrinology (대한내분비학회지) 
ISSN
 1015-6380 
Issue Date
2006
Keywords
Double pituitary adenomas ; Acromegaly ; IGF-1 ; Multiple pituitary tumors
Abstract
Acromegaly is a clinical syndrome, which is caused by an excess of growth hormone (GH), most commonly secreted from a pituitary solitary adenoma. However, our patient had bilateral GH-secreting pituitary tumors, the incidence of which has been reported in only 1.3 to 1.69% of all acromegalic patients. A 59-year-old female, with no family history of pituitary adenomas, demonstrated an increased level of serum insulin-like growth factor-1 (IGF-1), and GH not suppressed after 75 g oral glucose loading. On a preoperative MRI, only one pituitary tumor, measuring 1.1 × 0.7 cm, could be observed using sellar MRI. After surgical resection of the tumor, her headache and myalgia were sustained, and the IGF-1 level was still in a high titer. Therefore, a follow-up sellar MRI was taken, and a 0.6 × 0.7 cm sized newly growing pituitary tumor was found on the other side. With a retrospective review of radiological examinations, the patient was found to have bilateral tumors. The 0.3 cm sized tumor on the left was too small to be detected on the preoperative MRI. As the patient preferred medical treatment after surgery, she was treated with sandostatin analogues. Acromegaly with bilateral GH-secreting pituitary tumors, is a very rare disease, with no previous case having been reported in Korea. Herein, we report the case with a review of the literature
Files in This Item:
T200600418.pdf Download
DOI
10.3803/jkes.2006.21.1.53
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Rae(김경래)
Ahn, Chul Woo(안철우) ORCID logo https://orcid.org/0000-0003-3733-7486
Lee, Hyun Chul(이현철)
Lim, Sung Kil(임승길)
Cha, Bong Soo(차봉수) ORCID logo https://orcid.org/0000-0003-0542-2854
Hong, Soon Won(홍순원) ORCID logo https://orcid.org/0000-0002-0324-2414
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/109269
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