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제2형 당뇨병환자에서 내장지방 및 피하지방과 작고 밀집한 저밀도 지단백 콜레스테롤 농도와의 관계

Other Titles
 The Relationship between Visceral & Subcutaneous Fat and Small Dense Low Density Lipoprotein Cholesterol Concentration in Type 2 Diabetic Patients 
Authors
 심완섭  ;  김수경  ;  김혜진  ;  강은석  ;  안철우  ;  임승길  ;  이현철  ;  차봉수 
Citation
 Journal of Korean Diabetes Association (당뇨병), Vol.30(3) : 207-216, 2006 
Journal Title
 Journal of Korean Diabetes Association (당뇨병) 
ISSN
 2233-6079 
Issue Date
2006
Keywords
Small dense LDL-C ; Subcutaneous fat ; Type 2 diabetes mellitus ; Ultrasonography ; Visceral fat
Abstract
Background: Visceral obesity is closely associated with cardiovascular disease (CVD). Small dense (sd) LDL is closely associated with CVD. The aim of this study was to evaluate the relationship between visceral and subcutaneous fat accumulation and sd LDL-C concentration. Methods: 264 type 2 diabetic patients underwent ultrasonography to estimate visceral & subcutaneous fat accumulation and sd LDL-C concentrations were measured. Results: BMI, total cholesterol, sd LDL-C concentration and percentage of sd LDL-C were higher in highest tertile of visceral fat length in male than those in lowest tertile. BMI, total cholesterol, triglyceride, LDL-C, sd LDL-C concentration and percentage of sd LDL-C were higher in highest tertile of visceral fat length in female than those in lowest tertile. But sd LDL-C concentration and percentage of sd LDL-C were not different among three groups based on the tertile of subcutaneous fat length in male and female. Visceral fat length was correlated with sd LDL-C concentration and percentage of sd LDL-C, total cholesterol, triglyceride, LDL-C, but negatively with percentage of large buoyant LDL-C and HDL-C after adjustment of age, sex and BMI. Subcutaneous fat length was not correlated with sd LDL-C and percentage of sd LDL-C, total cholesterol, triglyceride, HDL-C and LDL-C. Conclusion: The association between visceral fat length and sd LDL-C could be a factor that explains the association between visceral obesity and CVD.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Eun Seok(강은석) ORCID logo https://orcid.org/0000-0002-0364-4675
Ahn, Chul Woo(안철우) ORCID logo https://orcid.org/0000-0003-3733-7486
Lee, Hyun Chul(이현철)
Lim, Sung Kil(임승길)
Cha, Bong Soo(차봉수) ORCID logo https://orcid.org/0000-0003-0542-2854
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/109263
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