Cited 21 times in
Characteristics of muscle fibers reconstituted in the regeneration process of masseter muscle in an mdx mouse model of muscular dystrophy
DC Field | Value | Language |
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dc.contributor.author | 김희진 | - |
dc.date.accessioned | 2015-06-10T12:03:20Z | - |
dc.date.available | 2015-06-10T12:03:20Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0142-4319 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/109109 | - |
dc.description.abstract | Mdx mice, which lack dystrophin, were examined for changes in the properties of muscle fibers in the growth process of the masseter muscle at the morphological, protein and transcriptional levels. The slow-type isoform, MyHC-1, and the fast-type isoforms, MyHC-2a, MyHC-2d and MyHC-2b, were examined at the protein and the transcriptional level. Morphological examination showed that in the mdx mouse masseter muscle, degeneration, necrosis, and regeneration occurred, particularly at the age of 4 weeks, and many regenerated muscle fibers with centrally located nuclei were observed at the age of 9 weeks. The results of examination at the protein and the transcriptional level showed that in the process of muscle fiber degeneration, necrosis, and regeneration, the mdx mouse masseter muscle acquires muscle fiber characteristics entirely different from those in the normal mouse masseter muscle. In particular, MyHC-1, which is rarely found in normal mice, was very strongly expressed. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 235~240 | - |
dc.relation.isPartOf | JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Masseter Muscle/metabolism | - |
dc.subject.MESH | Masseter Muscle/physiology* | - |
dc.subject.MESH | Masseter Muscle/ultrastructure | - |
dc.subject.MESH | Mice | - |
dc.subject.MESH | Mice, Inbred mdx | - |
dc.subject.MESH | Muscle Fibers, Skeletal/metabolism* | - |
dc.subject.MESH | Muscular Dystrophies/metabolism* | - |
dc.subject.MESH | Muscular Dystrophy, Animal | - |
dc.subject.MESH | Myosin Heavy Chains/genetics | - |
dc.subject.MESH | Myosin Heavy Chains/metabolism* | - |
dc.subject.MESH | Protein Isoforms/genetics | - |
dc.subject.MESH | Protein Isoforms/metabolism | - |
dc.subject.MESH | RNA, Messenger/metabolism | - |
dc.subject.MESH | Regeneration* | - |
dc.title | Characteristics of muscle fibers reconstituted in the regeneration process of masseter muscle in an mdx mouse model of muscular dystrophy | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral Biology (구강생물학) | - |
dc.contributor.googleauthor | Won-Hyung Lee | - |
dc.contributor.googleauthor | Shinichi Abe | - |
dc.contributor.googleauthor | Hee-Jin Kim | - |
dc.contributor.googleauthor | Akinobu Usami | - |
dc.contributor.googleauthor | Atsuro Honda | - |
dc.contributor.googleauthor | Koji Sakiyama | - |
dc.contributor.googleauthor | Yoshinobu Ide | - |
dc.identifier.doi | 10.1007/s10974-006-9066-5 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01225 | - |
dc.relation.journalcode | J01613 | - |
dc.identifier.eissn | 1573-2657 | - |
dc.identifier.pmid | 16752197 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs10974-006-9066-5 | - |
dc.subject.keyword | Myosin heavy chain | - |
dc.subject.keyword | MyHC2a | - |
dc.subject.keyword | MyHC2b | - |
dc.subject.keyword | Mdx | - |
dc.subject.keyword | LightCycler® | - |
dc.contributor.alternativeName | Kim, Hee Jin | - |
dc.contributor.affiliatedAuthor | Kim, Hee Jin | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 27 | - |
dc.citation.number | 3-4 | - |
dc.citation.startPage | 235 | - |
dc.citation.endPage | 240 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, Vol.27(3-4) : 235-240, 2006 | - |
dc.identifier.rimsid | 50592 | - |
dc.type.rims | ART | - |
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