Cited 94 times in
Effects of lifestyle modification on metabolic parameters and carotid intima-media thickness in patients with type 2 diabetes mellitus
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강은석 | - |
dc.contributor.author | 안철우 | - |
dc.contributor.author | 유지수 | - |
dc.contributor.author | 이현철 | - |
dc.contributor.author | 차봉수 | - |
dc.date.accessioned | 2015-06-10T11:56:36Z | - |
dc.date.available | 2015-06-10T11:56:36Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0026-0495 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/108902 | - |
dc.description.abstract | The aim of this study was to examine the effects of a 6-month intensive lifestyle modification intervention on metabolic parameters and carotid intima-media thickness (IMT) in patients with type 2 diabetes mellitus. Fifty-eight subjects with type 2 diabetes mellitus were randomly assigned to the intervention group or the control group. The subjects in the intervention group participated in a 16-week intensive lifestyle modification program and subsequent monthly meetings during the 6-month study period. Control subjects received basic dietary education and usual care. Anthropometric data, metabolic parameters, and carotid IMT were examined before the intervention and after 6 months. Lifestyle modification intervention group patients showed a significant reduction in HbA1c (−1.0% ± 1.3% vs +0.1% ± 1.2%, P = .002), fasting blood glucose (−1.6 ± 1.5 vs +0.3 ± 2.5 mmol/L, P = .001), and 2-hour postprandial plasma glucose (−2.1 ± 2.5 vs +0.8 ± 4.4 mmol/L, P = .003) compared with control patients after 6 months. Body weight (−2.0 ± 2.6 vs +0.2 ± 1.7 kg, P = .001), body mass index (−0.8 ± 1.0 vs 0.0 ± 0.8 kg/m2, P = .003), and systolic blood pressure (−8.2 ± 15.9 vs +0.4 ± 14.1 mm Hg, P = .041) were significantly decreased in the intervention group. A significantly reduced carotid mean IMT progression was seen in the intervention group after 6 months (−0.040 ± 0.136 vs +0.083 ± 0.167 mm, P = .007). Changes in HbA1c (r = 0.34, P = .028), fasting plasma glucose (r = 0.31, P = .045), and 2-hour postprandial plasma glucose (r = 0.37, P = .015) correlated with the mean carotid IMT change after adjustment for age and sex. In conclusion, a 6-month intensive lifestyle modification intervention in patients with type 2 diabetes mellitus resulted in improved glycemic control and decreased progression of carotid IMT. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1053~1059 | - |
dc.relation.isPartOf | METABOLISM-CLINICAL AND EXPERIMENTAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Anthropometry | - |
dc.subject.MESH | Behavior Therapy | - |
dc.subject.MESH | Blood Glucose/metabolism | - |
dc.subject.MESH | Blood Pressure/physiology | - |
dc.subject.MESH | Body Weight/physiology | - |
dc.subject.MESH | Carotid Arteries/diagnostic imaging | - |
dc.subject.MESH | Carotid Arteries/pathology* | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/metabolism | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/pathology* | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/therapy* | - |
dc.subject.MESH | Diet | - |
dc.subject.MESH | Dyslipidemias/therapy | - |
dc.subject.MESH | Echocardiography | - |
dc.subject.MESH | Exercise | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypoglycemic Agents/therapeutic use | - |
dc.subject.MESH | Life Style* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Obesity/complications | - |
dc.subject.MESH | Obesity/therapy | - |
dc.subject.MESH | Patient Compliance | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Effects of lifestyle modification on metabolic parameters and carotid intima-media thickness in patients with type 2 diabetes mellitus | - |
dc.type | Article | - |
dc.contributor.college | College of Nursing (간호대학) | - |
dc.contributor.department | Dept. of Nursing Environment Systems (임상간호과학과) | - |
dc.contributor.googleauthor | So Hun Kim | - |
dc.contributor.googleauthor | Suk Jeong Lee | - |
dc.contributor.googleauthor | Eun Seok Kang | - |
dc.contributor.googleauthor | Shinae Kang | - |
dc.contributor.googleauthor | Kyu Yeon Hur | - |
dc.contributor.googleauthor | Hyun Joo Lee | - |
dc.contributor.googleauthor | Chul Woo Ahn | - |
dc.contributor.googleauthor | Bong Soo Cha | - |
dc.contributor.googleauthor | Ji Soo Yoo | - |
dc.contributor.googleauthor | Hyun Chul Lee | - |
dc.identifier.doi | 10.1016/j.metabol.2006.03.017 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00068 | - |
dc.contributor.localId | A02270 | - |
dc.contributor.localId | A02514 | - |
dc.contributor.localId | A03301 | - |
dc.contributor.localId | A03996 | - |
dc.relation.journalcode | J02223 | - |
dc.identifier.eissn | 1532-8600 | - |
dc.identifier.pmid | 16839841 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S002604950600120X | - |
dc.contributor.alternativeName | Kang, Eun Seok | - |
dc.contributor.alternativeName | Ahn, Chul Woo | - |
dc.contributor.alternativeName | Yoo, Ji Soo | - |
dc.contributor.alternativeName | Lee, Hyun Chul | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | Kang, Eun Seok | - |
dc.contributor.affiliatedAuthor | Ahn, Chul Woo | - |
dc.contributor.affiliatedAuthor | Yoo, Ji Soo | - |
dc.contributor.affiliatedAuthor | Lee, Hyun Chul | - |
dc.contributor.affiliatedAuthor | Cha, Bong Soo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 55 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1053 | - |
dc.citation.endPage | 1059 | - |
dc.identifier.bibliographicCitation | METABOLISM-CLINICAL AND EXPERIMENTAL, Vol.55(8) : 1053-1059, 2006 | - |
dc.identifier.rimsid | 49953 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.