Cited 10 times in
Combined surgery and postoperative radiotherapy for oropharyngeal squamous cell carcinoma in Korea: analysis of 110 cases
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 유대현 | - |
dc.contributor.author | 최은창 | - |
dc.date.accessioned | 2015-05-19T17:42:16Z | - |
dc.date.available | 2015-05-19T17:42:16Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0901-5027 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/108656 | - |
dc.description.abstract | The treatment of oropharyngeal squamous cell carcinoma (OSCC) remains controversial. This study reviews the authors' experience of treating OSCC, evaluates the oncologic outcome and assesses the factors affecting local/regional recurrence. A retrospective analysis of 110 consecutive OSCC patients treated primarily by surgery and/or postoperative radiotherapy was carried out. 82% of patients had advanced disease (stage III or IV). The 5-year overall survival and disease specific survival rates (DSSR) were 58% and 65%, respectively. The DSSR of the soft palate or posterior pharyngeal wall, tonsillar area, and base of tongue were 80%, 62%, and 51%, respectively (P<0.05). The 5-year DSSR according to the American Joint Committee on Cancer stages was 94% for early stage and 56% for advanced stage (P<0.05). The overall recurrence rate was 38% (42 patients). The most frequent site of recurrence was the neck (46%). Only 14% of patients with recurrences were treated successfully. Positive resection margins and the presence of pathologic lymph nodes influenced the recurrence at the primary lesion and in the neck, respectively, in a statistically significant manner. Surgery and postoperative radiotherapy provided a superior outcome in patients with advanced OSCC. A randomized study is required to assess the oncologic and functional superiority of surgery or chemoradiation. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1099~1105 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Carcinoma, Squamous Cell/radiotherapy | - |
dc.subject.MESH | Carcinoma, Squamous Cell/secondary | - |
dc.subject.MESH | Carcinoma, Squamous Cell/surgery* | - |
dc.subject.MESH | Disease-Free Survival | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Lymphatic Metastasis/pathology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neck/pathology | - |
dc.subject.MESH | Neck Dissection | - |
dc.subject.MESH | Neoadjuvant Therapy* | - |
dc.subject.MESH | Neoplasm Recurrence, Local/pathology | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Oropharyngeal Neoplasms/radiotherapy | - |
dc.subject.MESH | Oropharyngeal Neoplasms/surgery* | - |
dc.subject.MESH | Palate, Soft/radiation effects | - |
dc.subject.MESH | Palate, Soft/surgery | - |
dc.subject.MESH | Radiotherapy Dosage | - |
dc.subject.MESH | Radiotherapy, Adjuvant | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Salvage Therapy | - |
dc.subject.MESH | Survival Rate | - |
dc.subject.MESH | Tongue Neoplasms/radiotherapy | - |
dc.subject.MESH | Tongue Neoplasms/surgery | - |
dc.subject.MESH | Tonsillar Neoplasms/radiotherapy | - |
dc.subject.MESH | Tonsillar Neoplasms/surgery | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Combined surgery and postoperative radiotherapy for oropharyngeal squamous cell carcinoma in Korea: analysis of 110 cases | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Otorhinolaryngology (이비인후과학) | - |
dc.contributor.googleauthor | Y. C. Lim | - |
dc.contributor.googleauthor | H. J. Hong | - |
dc.contributor.googleauthor | S. J. Baek | - |
dc.contributor.googleauthor | J. H. Park | - |
dc.contributor.googleauthor | G. E. Kim | - |
dc.contributor.googleauthor | C. G. Lee | - |
dc.contributor.googleauthor | D. H. Lew | - |
dc.contributor.googleauthor | W. J. Lee | - |
dc.contributor.googleauthor | E. C. Choi | - |
dc.identifier.doi | 10.1016/j.ijom.2008.07.002 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02459 | - |
dc.contributor.localId | A04161 | - |
dc.relation.journalcode | J01143 | - |
dc.identifier.eissn | 1399-0020 | - |
dc.identifier.pmid | 18722091 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0901502708002816 | - |
dc.subject.keyword | oropharyx | - |
dc.subject.keyword | squamous cell carcinoma | - |
dc.subject.keyword | treatment | - |
dc.subject.keyword | surgery | - |
dc.contributor.alternativeName | Lew, Dae Hyun | - |
dc.contributor.alternativeName | Choi, Eun Chang | - |
dc.contributor.affiliatedAuthor | Lew, Dae Hyun | - |
dc.contributor.affiliatedAuthor | Choi, Eun Chang | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 37 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1099 | - |
dc.citation.endPage | 1105 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, Vol.37(12) : 1099-1105, 2008 | - |
dc.identifier.rimsid | 37159 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.