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갈색세포종에서 18FDG의 전신 갈색지방조직 섭취를 보인 증례 1예

Other Titles
 Diffuse 18F-fluoro-2-deoxy-D-glucose uptake of brown adipose tissue in pheochromocytoma due to increased sympathetic nervous system activity 
Authors
 홍수정  ;  김경민  ;  이유미  ;  윤미진  ;  이종두  ;  이은직  ;  임승길 
Citation
 Korean Journal of Medicine, Vol.75(s3) : 858-861, 2008 
Journal Title
 Korean Journal of Medicine 
ISSN
 1738-9364 
Issue Date
2008
Keywords
Pheochromocytoma ; Brown adipose tissue ; Catecholamines ; Positron-emission tomography
Abstract
A pheochromocytoma is a tumor of chromaffin cells that originates from either the adrenal medulla or extra-adrenal sympathetic tissues. The diagnosis of pheochromocytoma is based on elevated concentrations of plasma and urinary catecholamines or their metabolites. In most patients, the anatomic localization of the tumor is determined with computed tomography or magnetic resonance imaging. However, metaiodobenzylguanidine-scintigraphy or positron emission tomography (PET) can also easily identify the foci of neuroendocrine tumors. We diagnosed a patient with pheochromocytoma and high urinary norepinephrine levels, whose PET images revealed diffuse 18F-fluoro-2-deoxy-D-glucose (18FDG) accumulation in the shoulder, lower neck, and perivertebral area. The regions of 18FDG uptake corresponded to the location of human brown adipose tissue (BAT), which is minimally active in adults. It is thought that excessive sympathetic stimulation by high circulating catecholamine concentrations augmented the metabolic activity and tracer uptake in the BAT. This uptake in the BAT was normalized after surgical resection
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Min(김경민)
Rhee, Yumie(이유미) ORCID logo https://orcid.org/0000-0003-4227-5638
Lee, Eun Jig(이은직) ORCID logo https://orcid.org/0000-0002-9876-8370
Lim, Sung Kil(임승길)
Hong, Soo Jung(홍수정)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/108462
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